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News MUDr. Petra Garnolová: The combination of medical cannabis with other analgesics is the ideal way to achieve the best effect with the fewest side effects

Medical cannabis is gradually finding its way to many patients with various ailments, including those with unmanageable and hard-to-influence chronic pain. For them, this therapy can offer a new chance at a quality life despite severe or terminal illness. A relatively new form that brings additional benefits is the extract of medical cannabis. We spoke with MUDr. Petra Garnolová, a specialist in clinical oncology and palliative medicine, about why it is worth considering not only as part of analgesic therapy and her experiences from real practice.

Source: Medical Cannabis 8. 1. 2024

News CASE STUDY: Oral Semaglutide in a Young Diabetic = Weight Loss and CV Risk Reduction, Better Adherence and Treatment Comfort

Diabetologist MUDr. Tomáš Pfohl from the Regional Hospital Liberec illustrates the benefits of therapy with oral semaglutide in a relatively young diabetic patient with type 2 DM after unsatisfactory disease compensation was not achieved with a combination of gliptin and metformin.

Source: Modern Treatment of Diabetes with GLP-1 Analogues 10. 6. 2024

Články časopisu Chronic lymphocytic leukaemia –⁠ contemporary application of modern prognostic and predictive markers in diagnostics

Author of the article: Š. Pospíšilová, M. Jarošová, M. Doubek Source: Transfuze a hematologie dnes | 1/2019 29. 3. 2019

News Patient with Diabetes: When to Follow Up and When to Refer to a Specialist?

It is most often the general practitioner (GP) who first diagnoses diabetes. Whether during preventive check-ups, preoperative examinations, or based on the patient's clinical issues. After diagnosing diabetes, however, the GP faces a difficult decision: Will they continue to monitor and treat the patient themselves, or will they refer them to a diabetologist?

Source: Diabetes 6. 12. 2020

News How do patients perceive the change in appearance of chronically used medications and to what extent does it lead to non-adherence to therapy?

Doctors regularly encounter patients in their offices who complain about changes in the appearance of their chronically used medications. Such a change can even be the cause of non-adherence to treatment. Interesting findings on this topic were brought by an American survey aimed at identifying the preferences, experiences, and reactions of patients and pharmacists related to changes in the appearance of medications.

Source: Cardiovascular Continuum 23. 2. 2022

News If Suicides Were COVID-19... or Why We Still Overlook a Significant Cause of Premature Deaths?

More than a year since the start of the pandemic, the SARS-CoV-2 coronavirus has claimed 2.8 million lives globally, with 127 million recorded cases of COVID-19 (as of March 29, 2021). According to World Health Organization (WHO) data, there are 800,000 suicides annually, with suicide attempts being up to 20 times more frequent, totaling over 16 million. Given our current focus on physical health, are we overlooking the extent and importance of mental health issues in the population? This question has been raised by several experts from different countries in their submission to the February issue of The Journal of Clinical Psychiatry.

Source: Depression and Anxiety 30. 3. 2021

News Fatigue and Quality of Life in Patients with Primary Biliary Cholangitis

Fatigue is the most common symptom of primary biliary cholangitis (PBC). Its occurrence significantly impacts the health-related quality of life of patients.

Source: Primary Biliary Cholangitis 8. 3. 2021

News Why Are Mucolytics Beneficial for Patients with COPD?

Part of the clinical picture of chronic obstructive pulmonary disease (COPD) includes mucus hypersecretion in the airways and its impaired clearance, resulting in a chronic productive cough. Mucus production requires management, just like dyspnea and cough. But what can be expected from mucolytic treatment?

Source: Cough Therapy 15. 4. 2021

News Variability of COPD Symptoms During the Day and Impact on Patients' Morning Routine –⁠ Survey Results

Chronic obstructive pulmonary disease (COPD) is viewed, unlike bronchial asthma, as a condition with a more chronic course and less variability of symptoms throughout the day. The study presented below aimed to clarify whether these patients experience deterioration at certain times of the day and how this affects their daily lives.

Source: COPD 7. 9. 2021

Články časopisu The present and future of metabolic surgery

Author of the article: P. Holéczy, M. Bužga, E. Machytka Source: Rozhledy v chirurgii | 2/2019 21. 2. 2019

News What situations can arise in PBC treatment with obeticholic acid? Answers provided by case studies from real practice at CKTCH

The Hradec Gastroenterology Days 2023 were traditionally held in March at the Educational Center of the Faculty of Medicine, Charles University, in the area of University Hospital Hradec Králové. The expert program included a lecture by MUDr. Libuše Husová, Ph.D., from the Cardio-surgical and Transplant Surgery Center Brno (CKTCH), who highlighted various situations that can arise during the treatment of primary biliary cholangitis (PBC) with three case studies.

Source: Primary Biliary Cholangitis 25. 4. 2023

News Efficacy and Safety of Empagliflozin in Patients with Heart Failure with Preserved Ejection Fraction

Previous studies have shown that the antidiabetic drug empagliflozin reduces the risk of cardiovascular death or hospitalization for heart failure in patients with heart failure with reduced left ventricular ejection fraction (HFrEF), both in diabetics and non-diabetics. The aim of the EMPEROR-Preserved clinical trial was to supplement data on the efficacy and safety of empagliflozin in a population of patients with heart failure with preserved ejection fraction (HFpEF; EF LK > 40%).

Source: Heart Failure 27. 4. 2022

News Summary of Recommendations for the Treatment of Immune Thrombocytopenia in Pregnancy

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a temporary or permanent reduction in the number of platelets, leading to an increased risk of bleeding. It also occurs in 1-5 out of 10,000 pregnant women. We summarize recommendations for the treatment of these patients.

Source: Immune Thrombocytopenia 28. 3. 2021

News Prof. Petra Lišková: Prevention of Dry Eye Syndrome is Difficult but Not Impossible

Dry eye syndrome is one of the most common ophthalmological problems, and its incidence is rising. Ophthalmologist Prof. MUDr. Petra Lišková, Ph.D., from the Clinic of Pediatrics and Hereditary Metabolic Disorders of the First Faculty of Medicine, Charles University, and University Hospital in Prague, explains how these difficulties arise and why patients should visit an eye doctor rather than relying solely on self-treatment.

Source: Ophthalmologic Diseases 13. 3. 2023

News Expanded Hemodialysis and Its Impact on Reducing Hospitalization Rates and Medication Usage

The number of patients with end-stage kidney disease is increasing. New approaches and technological advancements in recent decades have contributed to improving hemodialysis treatment. Does the use of so-called expanded hemodialysis lead to better outcomes?

Source: Chronic Kidney Disease 30. 11. 2021