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News Intermittent Fasting May Carry Significant Health Risks

Results from an observational study presented at this year’s American Heart Association (AHA) Congress revealed surprising findings. Eating restricted to an 8-hour window daily—a popular form of intermittent fasting—may be associated with a significantly higher risk of cardiovascular (CV) death compared to regular eating within a 12–16-hour window.

Source: 29. 10. 2024

News Lactobacillus reuteri −⁠ a natural probiotic with lifelong significance

Probiotics are often given to newborns within the first few days of life to alleviate infantile colic. However, the role of probiotic treatment in protecting infants from infections, even into their adult life, is a growing area of research interest. Which natural probiotic strains have verified immunomodulatory properties and is it suitable to administer them alongside breast milk?

Source: GI, colic and microbiome 16. 2. 2021

News Ketogenic diet in MS patients as an aid to increase microbiota diversity and quantity

A recent study published in the journal Frontiers in Microbiology explores the role of gut microbiota in multiple sclerosis, specifically the changes in its quantity and the potential for influencing microbiota through a ketogenic diet.

Source: Multiple Sclerosis 21. 2. 2020

News How and when does the reaction to gluten begin in coeliac disease? A new Canadian study offers potential answers

As is well known, coeliac disease is a systemic autoimmune disorder characterised by damage to intestinal epithelial cells (IEC). Canadian researchers have sought to uncover the relationship between intestinal epithelial cells and T lymphocyte activation in this disease. The results of their work provide hope for the potential development of an effective therapy.

Source: 6. 11. 2024

News Change in Release of Medication Pradaxa

Dear Doctor,
We would like to inform you that from April 1, 2021, based on the decision of the State Institute for Drug Control (SÚKL), the release of the medication (LP) Pradaxa (dabigatran-etexilate) 150 and 110 mg in the indication “Prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation” will be changed to first-line treatment.

Source: Anticoagulant Treatment 31. 3. 2021

News Effect of 3 Different Doses of Trazodone on QT Interval Length

Patients diagnosed with depression often also suffer from cardiovascular diseases, including heart failure. Given the increased risk of death in such comorbid patients, the safety and efficacy of the antidepressant must be considered when choosing one.

Source: Depression and Anxiety 5. 10. 2020

News Levothyroxine and the Interchangeability of Preparations Containing It

Levothyroxine is a synthetic thyroid hormone used to treat patients with hypothyroidism, which affects approximately 1-2% of the younger population and increases with age, especially in women. Levothyroxine is a drug with a narrow therapeutic window, and its bioavailability is influenced by many factors, including consumed foods, medications, and beverages.

Source: Thyroid Disorders 6. 11. 2020

News What a Decade of Experience with Tapentadol Hydrochloride in Pain Treatment Has Shown

In an interview with Dr. Marek Hakl, Ph.D., from the Brno Pain Treatment Center, we focus on the role of tapentadol hydrochloride in the treatment of chronic pain. We discuss, among other things, its suitability for specific patients and the latest findings that confirm its excellent efficacy and fewer side effects compared to other opioids.

Source: Updates in Pain Treatment 12. 10. 2023

Články časopisu Depression in Selected Neurological Disorders

Author of the article: I. Štětkářová, J. Horáček Source: Česká a slovenská neurologie a neurochirurgie | 6/2016 10. 11. 2016

Články časopisu BENIGN DERMATOSIS OF PENIS

Author of the article: MUDr. David Němec Source: Urologické listy | 4/2005 4. 1. 2006

Články časopisu Fecal microbiota transplantation –⁠ past, present, and future

Author of the article: Stebel R., Vojtilová L., Husa P. Source: Gastroenterologie a hepatologie | 1/2020 25. 2. 2020

News Effect of Initiation of Warfarin Therapy on the Risk of Ischemic Stroke

Anticoagulant therapy is essential in patients with atrial fibrillation for the prevention of thromboembolic events. Warfarin is a highly effective anticoagulant, but the introduction of new oral anticoagulants (NOACs) has offered certain advantages over it. Shortly after starting warfarin therapy, patients have repeatedly been shown to have a paradoxically increased risk of developing ischemic stroke. The aim of the study presented below was to determine whether this increase in risk is associated with the initiation of anticoagulant therapy.

Source: Anticoagulant Treatment 17. 7. 2020

Články časopisu Definition of sepsis and septic shock

Author of the article: M. Holub Source: Klinická biochemie a metabolismus | 2/2018 10. 4. 2018

Články časopisu Balance disorders in patients with multiple sclerosis and possible rehabilitation therapy –⁠ current findings from controlled clinical trials

Author of the article: K. Novotná-, I. Menkyová, M. Janatová Source: Česká a slovenská neurologie a neurochirurgie | 2/2022 15. 5. 2022

Články časopisu Diabetes and Schizophrenia

Author of the article: L. Ustohal1ihash2 Source: Česká a slovenská neurologie a neurochirurgie | 1/2012 20. 1. 2012