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News 10 Properties and Benefits of Gliptins: How They Work and When to Prescribe Them
General practitioners can now prescribe oral antidiabetics from the group of gliptins to patients with type 2 diabetes. Their therapeutic options are significantly expanded in the care of these patients. In the following text, we briefly summarize the mechanism of action of gliptins and their advantages over other oral antidiabetics.Source: Diabetes 28. 8. 2020News How to Properly Treat Frostbite?
Frostbite, or congelation, is defined as an acute condition involving damage to the skin and subcutaneous tissues due to local cold, particularly at subzero temperatures. Treatment requires quality care. By choosing the right therapy, we can prevent complications that might otherwise threaten the patient with amputation of the affected part. The healing process is lengthy and requires patience from both the patient and the attending physician.Source: Wound Healing 7. 12. 2021News Metamizole – wide possibilities of an analgesic with a unique mechanism of action and different routes of administration
Metamizole is a non-addictive pyrazolone analgesic with antipyretic effects, which differs from other non-opioid analgesics by its spasmolytic action. It is indicated in monotherapy and in combinations for the treatment of severe acute and chronic pain. Its high analgesic efficacy is evidenced by a low number of patients needed to treat to achieve at least 50% pain relief in 4-6 hours. The favorable safety profile of metamizole is supported by more than 100 years of clinical experience.Source: Analgesia 30. 5. 2024News Generic Substitution of Levothyroxine in Practice
The active ingredient levothyroxine is found in a significant number of medicinal products (MP) in the Czech Republic. The question of its generic substitution remains current, primarily because the previously published data tend to call for caution due to possible adverse effects on the patient.Source: Thyroid Disorders 22. 2. 2024News Benefit of Oral Semaglutide for Patients with Type 2 Diabetes in the General Practitioner's Office
Oral semaglutide is a modern antidiabetic suitable within primary care for people with type 2 diabetes, primarily due to its comprehensive action that includes not only reducing blood glucose and body weight but also a number of other favorable non-glycemic effects.Source: Modern Treatment of Diabetes with GLP-1 Analogues 22. 5. 2024News FDA Warns Against Self-Monitoring Glucose Using Smartwatches. What About in Czechia?
On February 21st, the U.S. Food and Drug Administration (FDA) issued a warning aimed at diabetic patients who measure their blood glucose levels (or are considering doing so) using smartwatches or rings. The warning naturally also targeted attending physicians who might encounter this method of non-invasive measurement in their patients. The Czech diabetologists we spoke to have only come across a few cases of this so far. Nevertheless, many of them believe it is necessary to discuss the topic with diabetics preventively and to actively work with those who decide to use such methods.News Comprehensive View on Care for Patients with Urostomy
Thanks to improvements in surgical techniques and shorter hospital stays, patients with a stoma are returning to their home environment and to the care of outpatient doctors sooner. Quality care in the postoperative period is a crucial element in the prevention of complications, support of healing, and education of ostomy patients. Doctors caring for these patients should approach them comprehensively, considering all their needs and aspects.Source: Ostomy 28. 2. 2020News Glucagon for Intranasal Application Newly Available Also in the Czech Republic
Intramuscular administration of glucagon was until recently the only option for acute treatment of hypoglycemia with impaired consciousness at home. However, since July this year, the Baqsimi product – glucagon for intranasal application – is newly available in the Czech Republic.Source: Modern Treatment of Diabetes 15. 9. 2020News Levothyroxine and the Interchangeability of Preparations Containing It
Levothyroxine is a synthetic thyroid hormone used to treat patients with hypothyroidism, which affects approximately 1-2% of the younger population and increases with age, especially in women. Levothyroxine is a drug with a narrow therapeutic window, and its bioavailability is influenced by many factors, including consumed foods, medications, and beverages.Source: Thyroid Disorders 6. 11. 2020News Psilocybin Approved as of January 1. What Does This Mean in Practice?
As of January 1, 2026, a new legal framework has come into effect in the Czech Republic allowing the limited therapeutic use of psilocybin in patients with severe mental health conditions. This represents the first systematic step in translating the results of long-term clinical research on psychedelics into healthcare practice. How does this change clinical practice, and what should physicians know even if they do not provide this therapy themselves?Články časopisu How Do Courts Set Health Policy? The Case of the Colombian Constitutional Court
Source: PLOS Medicine | 2/2009 3. 2. 2009Články časopisu Mapping the Spread of Malaria Drug Resistance
Source: PLOS Medicine | 4/2009 28. 4. 2009Články časopisu Grading Quality of Evidence and Strength of Recommendations: A Perspective
Source: PLOS Medicine | 9/2009 8. 9. 2009Články časopisu The Cost of Pushing Pills: A New Estimate of Pharmaceutical Promotion Expenditures in the United States
Source: PLOS Medicine | 1/2008 29. 1. 2008
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