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News Comparison of Clinical Outcomes of TKA Implantation: ATTUNE vs. SIGMA

The ATTUNE total knee arthroplasty (TKA) system was introduced to the market in 2013 as a successor to the popular SIGMA system. The new type of knee endoprosthesis is designed to provide better stability and mobility than the previous implant. Several studies have evaluated the clinical outcomes of the implantation of both types of endoprostheses.

Source: Large Joints 7. 2. 2020

News How to Properly Treat Frostbite?

Frostbite, or congelation, is defined as an acute condition involving damage to the skin and subcutaneous tissues due to local cold, particularly at subzero temperatures. Treatment requires quality care. By choosing the right therapy, we can prevent complications that might otherwise threaten the patient with amputation of the affected part. The healing process is lengthy and requires patience from both the patient and the attending physician.

Source: Wound Healing 7. 12. 2021

News Epstein-Barr Virus –⁠ Is the Culprit of MS Revealed?

Could the Epstein-Barr virus hold the answer to the etiology of multiple sclerosis? A dataset of over 10 million American recruits offered intriguing insights. You may have encountered the conclusions of one of the most extensive studies in modern history in the media. Let's take a closer look at the work of Kjetil Bjornevik and his colleagues.

Source: Multiple Sclerosis 23. 5. 2022

News Reimbursement vs. Indication: Are They Clashing in Alzheimer's Disease?

Data from clinical trials and recommended procedures do not always align with insurance reimbursement criteria. Is this the case with Alzheimer's disease treatment?

Source: Cognitive in the treatment of Alzheimer's disease 17. 5. 2020

News Key for Patients with PBC are Timely Diagnosis and Assessment of Therapy Effectiveness

Primary biliary cholangitis (PBC) cannot be cured. It progresses slowly and over several decades leads to liver cirrhosis with all its potential consequences, including possible transplantation and the risk of premature death. The foundation of PBC pharmacotherapy is ursodeoxycholic acid (UDCA) and in recent years, obeticholic acid (OCA) has also been available, which European and Czech guidelines recommend as the second-line treatment. One of the symposiums at this year's XLVIII May Hepatology Days also focused on PBC and its therapy, including experiences from Czech practice.

Source: Primary Biliary Cholangitis 19. 7. 2021

News Metformin in Pregnancy and Its Safety Profile

In Finland, a comprehensive analysis of data from the national registry was conducted to assess whether exposure to metformin during intrauterine development is associated with an increased risk of long-term or short-term health problems.

Source: Modern Treatment of Diabetes 6. 6. 2022

News American Heart Association: Side Effects of Statins Overview and Context

The American Heart Association (AHA) report provides an updated summary of knowledge on the safety of statin use. Despite warnings appearing in professional literature and general media, it assures that statins are an effective and safe modality for treating hypercholesterolemia.

Source: Cardiovascular Risks 15. 4. 2020

News Urinary Incontinence in Old Age as the Most Frequent Medical Problem

In patients over 65 years of age, incontinence occurs more frequently than cancer or cardiovascular diseases. Urine leakage significantly reduces the quality of life for seniors, worsens their overall health, and isolates them from society. Therefore, doctors should participate in destigmatizing this problem and actively offer their help to seniors and their family members.

Source: Incontinence 9. 9. 2020

News Thanks to Buccolam, the reality of suppressing convulsive seizures in children and adolescents approaches parents' ideal management

What crosses the mind of a parent when they notice their epileptic child or adolescent is having a convulsive seizure? They want it to be over quickly and safely. What constitutes the integral part that makes this wish a reality? And how does the newest treatment modality, buccally administered midazolam (Buccolam), address these needs?

Source: Quick aid for acute convulsive seizures in children and adolescents 25. 10. 2023

News Prediction of Hypocalcemia Risk in Patients Treated with Denosumab and Active Form of Vitamin D

According to new work by Japanese authors, it appears that the risk factors for the development of hypocalcemia in patients treated with denosumab and calcitriol (the active form of vitamin D) are different from those when natural vitamin D is added to denosumab.

Source: Prevention of Bone Events 8. 6. 2023

News Effective antiosteoporotics from the aminobisphosphonate group can finally be prescribed by general practitioners from January 2024

Osteoporosis represents a serious societal problem generating numerous health and social complications as well as considerable economic costs. In the Czech Republic, it is estimated to affect 500−750 thousand people, or 5−7% of the population. From January 1, 2024, the prescription restriction for the indication and reimbursement conditions for the medicinal products Osagrand (ibandronic acid) and Risendros (risedronic acid) will be lifted, allowing general practitioners to prescribe them as well, under the prescription conditions listed below.

Source: Treatment of Osteoporosis 12. 12. 2023

News Pregabalin in Seniors Confirmed Its Safety and Effectiveness

A pooled analysis of 11 studies investigated the safety and effectiveness of pregabalin in seniors with neuropathic pain. Are the outcomes in these indicators different for older individuals than in the general population sample?

Source: Neuropathic Pain 25. 6. 2020

News FDA Warns Against Self-Monitoring Glucose Using Smartwatches. What About in Czechia?

On February 21st, the U.S. Food and Drug Administration (FDA) issued a warning aimed at diabetic patients who measure their blood glucose levels (or are considering doing so) using smartwatches or rings. The warning naturally also targeted attending physicians who might encounter this method of non-invasive measurement in their patients. The Czech diabetologists we spoke to have only come across a few cases of this so far. Nevertheless, many of them believe it is necessary to discuss the topic with diabetics preventively and to actively work with those who decide to use such methods.

Source: 12. 4. 2024

News Overview of Current Treatment Options for MRSA-Induced Pneumonia

Pneumonia caused by methicillin-resistant strains of Staphylococcus aureus (MRSA) remains a disease with high mortality requiring urgent treatment, whether it is a community-acquired or nosocomial infection. Italian authors published a review article at the beginning of 2022, describing the current available treatment modalities for this infection based on a literature survey.

Source: Anti-Infectives 8. 7. 2022

Články časopisu Predictors of combined hormone contraception choice between Czech and Slovak women

Author of the article: Tomáš Fait Source: Česká gynekologie | 3/2011 11. 7. 2011