Search results: (10000)
News Current Results of Brigatinib in the Treatment of Lung Cancer
The results of the primary analysis showed a significant extension of PFS in patients with non-small cell lung cancer (NSCLC) treated with brigatinib compared to crizotinib. The recently published secondary analysis confirms these results.
News Importance of Home Parenteral Therapy: ESPEN Recommendations from 2020
Home parenteral therapy currently plays a crucial role in the treatment and prevention of malnutrition in specific patient groups. The European Society for Clinical Nutrition and Metabolism (ESPEN) published updated guidelines for home parenteral therapy in 2020, based on current evidence and expert recommendations.
News Vitamins in Prevention and Treatment of COVID-19
Vitamin supplementation is an important part of therapy for various diseases, and it seems that they also play a significant role in the case of COVID-19. What kind of role? It's certainly not a panacea, but it's not something to be underestimated.
News Does Peritoneal Dialysis Have Its Place Even in Acute Cases?
In patients who urgently need to replace kidney function, hemodialysis traditionally played the role of the gold standard. Can peritoneal dialysis fully replace it?
News Safety of Urgent Initiation of Peritoneal Dialysis
In case of urgent need for kidney function replacement, hemodialysis (HD) with a temporary venous catheter has long been the standard solution. However, it has several disadvantages such as increased mortality or the risk of bacteremia and central venous stenosis. Additionally, multiple procedures are needed to create a permanent venous access. Therefore, there is a growing global interest in urgently initiated peritoneal dialysis (PD), with several clinical studies attesting to its safety, efficacy, and feasibility. However, little has been known about early PD complications and the long-term prognosis of patients in terms of technical and infectious complications.
News Metamizole in the Treatment of Acute Postoperative Pain
In many countries, metamizole is considered a first-choice non-opioid analgesic. The analysis presented below, published in the Cochrane Database of Systematic Reviews, examined the efficacy and safety of metamizole in the treatment of acute postoperative pain.
News Case of Heparin Allergy and Preventive Administration of Fondaparinux in Pregnancy – Case Study
The presented case study discusses a complicated case of a 40-year-old woman with essential thrombocythemia (ET), a history of intrauterine fetal death, and recurrent pulmonary embolism (PE). The patient developed an allergic reaction to low-molecular-weight heparin (LMWH) and was successfully managed with fondaparinux during pregnancy.
News INFOGRAPHIC: Prevention and Management of Hypotension During Sacubitril/Valsartan Treatment
Despite the undeniable benefits of sacubitril/valsartan in terms of morbidity and mortality in patients with chronic heart failure, its administration can be complicated by side effects. The most common of these is hypotension.
News Thrombocytopenia Following mRNA Vaccination Against SARS-CoV-2
In connection with the administration of mRNA-based vaccines against the SARS-CoV-2 coronavirus, cases of secondary immune thrombocytopenia (ITP) have been described. A commentary published by a large team of authors in the American Journal of Hematology described a series of cases of low platelet counts identified within 2 weeks of vaccination. The data was obtained from the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), the Department of Health and Human Services (HHS), and the Vaccine Adverse Event Reporting System (VAERS), as well as through direct communication with patients and their physicians.
News Options for Reducing or Discontinuing TPO-RA Therapy in ITP Patients − Expert Consensus
There are currently no clear recommendations regarding dose reduction or discontinuation of thrombopoietin receptor agonists (TPO-RA) in patients with immune thrombocytopenia (ITP). A consensus by British authors offers insights into current clinical practice and the related issues.
News Quality of Life of Hemophiliacs and Ways to Improve It
Determining the quality of life (QoL) also reflects the morbidity associated with the disease, in this case, hemophilia. In the study presented below, the authors focused on determining QoL in relation to socioeconomic and other characteristics.
News Comparison of EHL Products in the Treatment of Hemophilia A – Pharmacoeconomic Analysis
In the work presented below, whose results were recently published, a model combining pharmacokinetic and pharmacodynamic data was developed. With its help, the authors tried to compare the bleeding rates in hemophiliacs treated with various EHL products. At the same time, they focused on the cost-effectiveness of this treatment.
News Diosmin – Still an Important Modality in the Treatment of Venous Insufficiency
Chronic venous insufficiency is a highly prevalent disease in the Western population. Unfortunately, it remains without causal treatment. In the recommended therapeutic procedures, especially in the initial stages, compression treatment supplemented with pharmacotherapy plays a key role. This includes the administration of medicinal products containing micronized diosmin. The following text summarizes basic findings about its properties that predispose it to clinical use.
News Less Ventricular Arrhythmias and ICD Shocks After Introduction of Sacubitril/Valsartan
Is the decrease in the incidence of sudden cardiac death among patients using sacubitril/valsartan due to a lower risk of ventricular arrhythmias? And does it have anything to do with reverse left ventricular remodeling? A newly published study utilizing data from telemonitoring of patients with implanted devices focused on this.