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News Incontinence as a Consequence of Surgical Procedure on the Prostate

Despite the advent of new surgical methods, urinary incontinence after prostate procedures remains a clinically significant iatrogenic complication. For patients, it represents a significant stress factor that carries physical and psychosocial consequences.

Source: Incontinence 17. 4. 2020

News Positive Effect of Pregabalin Not Only on Neuropathic Pain in Patients with Spinal Cord Injury

Spinal cord injury is often accompanied by painful conditions. A study published in the prestigious journal Neurology demonstrated that administering pregabalin to these patients can bring more than just pain relief.

Source: Neuropathic Pain 18. 2. 2020

Články časopisu Autoimmune Liver Diseases in Children. Part I

Author of the article: P. Dědek Source: Česko-slovenská pediatrie | 12/2010 13. 12. 2010

News How Diabetes Shortens Life or Mortality of Patients with Type 2 Diabetes

Type 2 diabetes mellitus (DM) has a significant impact on overall mortality across age categories. Who is most affected by this disease in terms of age and gender, and what are the current trends in mortality among the diabetic population?

Source: Diabetes 17. 2. 2022

News Metamizole in Pain Therapy in the General Practitioner and Pediatric Office

Metamizole is a pyrazole analgesic-antipyretic with spasmolytic effects, indicated for the treatment of post-traumatic or postoperative pain, visceral colic, cancer pain, and high fever unresponsive to other treatments. The advantage of this drug is its good tolerance without serious adverse effects on the gastrointestinal system, no impact on platelet aggregation, and usability in adults and children of all ages.

Source: Updates in Pain Treatment 30. 3. 2023

News Oral Azacitidine Prolongs Survival of AML Patients Regardless of Measurable Residual Disease

Intensive chemotherapy for patients newly diagnosed with acute myeloid leukemia (AML) often achieves high remission rates, although these remissions are often only temporary. Consolidation therapy with azacitidine (AZA) extends post-remission survival and disease-free intervals.

Source: Acute Myeloid Leukemia 6. 6. 2023

News Analgesic Effects of Using Ringer's Solution in Wound Healing Management

Pain resulting from skin defects of various etiologies causes significant discomfort for the patient. However, wound care using Ringer's solution and the use of primary dressings, which include this solution to maintain a constant moist environment in the wound, can help address this problem.

Source: Wound Healing 25. 2. 2022

News Diosmin and Hesperidin: What Does Pharmacokinetics Show?

Flavonoids are plant-derived compounds that have a number of beneficial pharmacological effects. Among the most well-known flavonoids, alongside rutin, are diosmin and hesperidin, which are used as venotonics and vasoprotectives in chronic venous insufficiency (CVI).

Source: Venous Insufficiency 23. 4. 2020

News Odor in Incontinence is a Common Concern of Patients

Urinary incontinence represents a significant stigma, which usually deprives the affected person of all social contact, work and leisure activities, as well as intimate life. According to statistics, fears of odor contribute significantly to this isolation, almost in 40% of cases.

Source: Incontinence 9. 9. 2020

News Reference Intervals of Prostate Health Index (PHI) in Healthy Men

For more specific prostate cancer screening, apart from prostate-specific antigen (PSA), its free fraction (fPSA) and one of its precursors, [-2]proPSA (p2PSA), are used today. From these parameters, the so-called Prostate Health Index (PHI) can be calculated. However, reference intervals for these parameters in a healthy population were not known until now.

Source: Prostate Health Index 2. 4. 2020

News What a Decade of Experience with Tapentadol Hydrochloride in Pain Treatment Has Shown

In an interview with Dr. Marek Hakl, Ph.D., from the Brno Pain Treatment Center, we focus on the role of tapentadol hydrochloride in the treatment of chronic pain. We discuss, among other things, its suitability for specific patients and the latest findings that confirm its excellent efficacy and fewer side effects compared to other opioids.

Source: Updates in Pain Treatment 12. 10. 2023

News Interstitial Lung Processes and Their Fibrotic Progression

Interstitial lung processes (ILPs) include more than 200 clinical units that share diffuse involvement of lung tissue and thus have similar clinical, radiological, and functional findings. However, their broad differential diagnosis is particularly problematic.

Source: Progressive Interstitial Pulmonary Processes 10. 9. 2021

News Association between Hypothyroidism, Depression, and Anxiety Disorder –⁠ Results of Meta-Analyses

The prevalence of autoimmune thyroiditis in the USA ranges between 4 and 13%. Subclinical hypothyroidism affects 3–8.5% of the general population. Patients with this condition are at risk not only from somatic manifestations. The meta-analyses presented below examined the association between hypothyroidism and the incidence of psychiatric disorders –⁠ depressive and anxiety disorders. One of the meta-analyses also evaluated the effect of levothyroxine administration on the incidence of depression in individuals with subclinical hypothyroidism.

Source: Thyroid Disorders 6. 9. 2023

News The Role of the General Practitioner in the Care of Incontinent Patients

General practitioners are sometimes likened to frontline soldiers because they are usually the first to whom patients turn with their health issues. Taking care of incontinent patients is a daily routine for them. They should therefore be knowledgeable about basic diagnostics and treatment and be able to actively identify incontinent patients.

Source: Incontinence 2. 6. 2020

News Side Effects of Metformin: It's Not Just a Nocebo Effect?

If we were to name medications that have the greatest significance from a population standpoint, metformin would certainly be at the top of the list. We have known it for over fifty years and know a lot about it, including its negatives. But is it time to replace it with new drugs? Or is it worth staying with it?

Source: Modern Treatment of Diabetes 11. 9. 2020