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News Is It Necessary to Discontinue Dupilumab in Patients with Atopic Dermatitis During the COVID-19 Pandemic?

Italian authors described their experiences with remote treatment of 200 atopic dermatitis (AD) patients using dupilumab during the COVID-19 pandemic outbreak in spring 2020. Observations from clinical practice, published data, and pathophysiological considerations do not suggest an increased risk of SARS-CoV-2 infection in AD patients receiving this biological treatment.

Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation 14. 12. 2020

News Doc. Jiří Kubeš: The major benefit of proton therapy lies in protecting healthy tissues

Nearly 9,000 patients with oncological diseases have already undergone modern proton radiotherapy at the Proton Center in Prague. Which diagnoses are suitable for this treatment modality, what are its main benefits, and what is its place in the comprehensive therapy of malignant tumors? We discuss these topics with the chief physician of this medical facility, Doc. MUDr. Jiří Kubeš, Ph.D.

Source: Proton Radiotherapy 7. 3. 2023

News Fexofenadine –⁠ Non-Sedative and Immunomodulatory Antihistamine in the Treatment of Allergic Symptoms

One of the biggest limitations of traditional antihistamines is the sedative effect on the central nervous system. Newer antihistamines do not cause sedation, are not associated with serious side effects, and some also have immunomodulatory effects.

Source: Viral infections 3. 3. 2022

News Hypertrophic Cardiomyopathy: When Bigger Does Not Mean Better

Hypertrophic cardiomyopathy (HCM) is a hereditary disease that, in some patients, proceeds asymptomatically, while others struggle with arrhythmias or heart failure, and in some individuals, the first manifestation of the disease can be sudden cardiac death. More about the etiology and diagnosis of HCM is discussed in the following overview.

Source: Hypertrophic Cardiomyopathy (HCM) 7. 9. 2023

News Impact of Thyroid Dysfunction on the Cardiovascular System in Elderly Patients

The incidence of thyroid disease increases with age. In the Czech Republic, up to 5% of the population suffers from hypothyroidism, and the prevalence of hyperthyroidism is estimated at 0.2-1%. The following text discusses the impact of these thyroid disorders on the cardiovascular (CV) system in elderly patients.

Source: Thyroid Disorders 2. 11. 2020

Články časopisu Non-Hodgkin lymphomas in the Czech Republic

Author of the article: M. Trněný Source: Transfuze a hematologie dnes | 1/2019 29. 3. 2019

Články časopisu

Author of the article: Šárka Slabá, Iva Málková, Martin Wagenknecht, Karel D. Riegel, Lukáš Junek, Judita Lorencová, Jitka Herlesová, Veronika Koch Ondrová, Pracovní Skupina Psychologické Sekce České Obezitologické Společnosti Čls Jep Source: Časopis lékařů českých | 3-4/2020 31. 7. 2020

News Minimally Invasive Treatment of Pilonidal Sinus: Laser and Negative Pressure Therapy as a Gentle and Effective Modality

The increasing incidence of pilonidal sinus contributes to the development of new treatment methods. Experiences from AGEL Hospital Přerov show that the methods SiLaC (sinus laser ablation of the cyst) and NPWT (negative pressure wound therapy) represent a gentle and effective approach for pilonidal sinus, accelerating treatment and subsequent recovery.

Source: Wound Healing 24. 11. 2023

News Prof. Petr Marusič: Is the Success of Therapy Changing with the Arrival of New Antiepileptics?

At the XXV. postgraduate course in epileptology, 'Jiří Dolanský Days', prof. MUDr. Petr Marusič, Ph.D., from the Neurological Clinic of the 2nd Faculty of Medicine, Charles University, and Motol University Hospital, lectured on the topic of changes in the efficacy of epilepsy treatment with the arrival of new anti-seizure medications.

Source: Epilepsy 2. 12. 2022

Články časopisu

Author of the article: Petr Klement, Jan Hřídel Source: Časopis lékařů českých | 3/2018 27. 6. 2018

News Low-Molecular-Weight Heparins in Thromboprophylaxis After Major Orthopedic and Traumatological Procedures According to Current Recommendations

Patients after major orthopedic and traumatological procedures are at high risk of thromboembolic disease. This is especially true for people undergoing hip and knee replacement or patients with a proximal femur fracture and severe lower limb injury. The routine implementation of pharmacological thromboprophylaxis, such as low-molecular-weight heparins, is currently the gold standard in perioperative care in these cases.

Source: Thromboprophylaxis 20. 6. 2022

News Inosine pranobex in the treatment of influenza and other respiratory infections of viral etiology

The antiviral inosine pranobex is a clinically proven immunomodulator for the treatment of patients from 1 year of age, indicated for a wide range of diseases with manifestations of immune insufficiency and viral infections. It acts by a direct antiviral effect, modulates the immune system, and also finds application in the treatment of acute viral respiratory diseases, such as influenza and other seasonal viral infections.

Source: Viral infections 24. 2. 2022

News With Prof. Pavel Žák about Current Trends and Future Perspectives in Bone Marrow Transplantation and the Role of Carmustine in this Context

Hematopoietic stem cell transplantation has an indispensable place in the treatment of hemato-oncological diseases. We discuss current trends in this area, the significance and benefits of carmustine, the choice between BEAM and TEAM regimens, and the future of bone marrow transplantation in the context of new technologies with the head of the 4th Department of Hematology of the Faculty of Medicine, Charles University and University Hospital Hradec Králové, Prof. MUDr. Pavel Žák, Ph.D.

Source: Oncological Treatment 10. 6. 2024

News Fixed Combination of Candesartan/Amlodipine in the Treatment of Arterial Hypertension

Arterial hypertension is a significant cardiovascular risk factor. A variety of antihypertensives are used in therapy, both in monotherapy and combination treatment. Often, it is necessary to treat patients with a combination of multiple antihypertensives to achieve satisfactory blood pressure values. A popular fixed combination with a favorable pharmacodynamic and pharmacokinetic profile is the combination of candesartan and amlodipine, whose effects have been verified by numerous extensive clinical studies.

Source: Sartans in the Treatment of Hypertension 19. 1. 2021

News Combination of Arterial Hypertension and Increased Heart Rate as a Significant Cardiovascular Risk Factor

Heart rate is one of the basic vital signs that should be regularly measured. Sinus tachycardia can be physiological under certain conditions. However, a patient with resting tachycardia should always be examined, as tachycardia can be a symptom of a serious health problem. Especially in patients with arterial hypertension, a rapid heart rate significantly increases cardiovascular risk.

Source: Cardiovascular Continuum 23. 11. 2020