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News Reasons for Nonadherence to Statin Therapy - Survey Results Among Patients
Adherence to statin therapy remains suboptimal despite its proven benefits in reducing cardiovascular risk in individuals with dyslipidemia. Recently published survey results conducted among patients prescribed statins have identified barriers preventing proper adherence to this treatment.
News New Treatment Options for Hemophilia Come with Discussions on Important Issues
The organizing committee of this year's virtual congress of the European Association for Haemophilia and Allied Disorders (EAHAD 2021) promised in the opening speech a "showcase of the latest innovations and advances in the field of hemophilia and bleeding disorders." The program naturally included discussions on current research findings and practical experiences. Topics included the potential role of coagulation factor VIII even with non-factor therapies and the importance of monitoring the success of new therapeutic approaches.
News Summary Analysis of HAVEN 1–4 and Patient Case Studies from ÚHKT
MUDr. Věra Geierová from the Institute of Hematology and Blood Transfusion in Prague prepared a summary of what was discussed about emicizumab during the ASH 2020 congress for this year's Prague Hematology Days. In this context, she highlighted the comprehensive analysis of phase 3 HAVEN 1–4 studies, which assessed the safety and efficacy of emicizumab in individuals with hemophilia A with or without FVIII inhibitors.
News Interactive Case Study of a Patient with Severe Hemophilia A - Experience from Slovenia
Assoc. Prof. Dr. Irena Preložnik Zupan (University Medical Centre Ljubljana) describes an interactive case study of a patient with severe hemophilia A and progressive cataracts in both eyes.
News How does Benzalkonium Chloride and Prostaglandins Affect Meibomian Gland Epithelial Cells?
Benzalkonium chloride is commonly used in eye drops intended for glaucoma treatment due to its preservative effect. However, in recent years, it has been shown to cause damage to both superficial and deeper eye tissues and also provoke other difficulties. The study presented below examined its effect on the epithelium of the Meibomian glands.
News Effect of Prostaglandin Analogues With and Without Preservatives on Meibomian Glands in Glaucoma Patients
Prostaglandin analogues (PGA) have become a standard in the treatment of open-angle glaucoma. However, their long-term use may be associated with eye irritation or damage to the Meibomian glands. The study presented below aimed to determine whether these changes are directly caused by PGAs or the preservatives in the eye drops.
News Frequency of Mutations in Genes Predisposing to Ovarian Cancer in the Czech Population
The authors of a Czech study evaluating the occurrence of mutations in tumor-predisposing genes for ovarian cancer hypothesized that if their occurrence in patients with this diagnosis was significant, identifying carriers of these mutations could help reduce the prevalence and mortality of this disease given the absence of other screening tools.
News Factors Influencing the Occurrence of Prosthetic Stomatitis in Patients with Complete Denture
Dental dentures are removable replacements made for partial or complete loss of teeth. Quality denture treatment is a long-lasting process in which oral hygiene and denture hygiene play a key role.
News San Antonio: Results of Breast Cancer Treatment with Combination of Pertuzumab, Trastuzumab, and AI After 6 Years
The virtual conference dedicated to breast cancer, which took place December 8–11 in San Antonio, USA (San Antonio Breast Cancer Symposium; SABCS 2020), presented, among other things, the results of the final analysis of the multicenter randomized open-label PERTAIN study.
News Virtual Echocardiography as a Potential Screening Tool for the Diagnosis of Primary Pulmonary Hypertension
Primary pulmonary hypertension disease is associated with a poor prognosis. Early diagnosis and the implementation of specific therapy are necessary to improve patients' prospects. In the near future, virtual echocardiography, which has shown good results in published studies, may become a valuable screening tool.
News How to Prevent and Treat Thromboembolic Disease in Cancer Patients
Malignancy is one of the risk factors for the development of thromboembolic disease (TED). Venous thromboembolism is considered the second most common cause of death in cancer patients, with the top cause being the cancer itself. Therefore, optimal treatment and timely prevention of these complications is very important.
News Thromboprophylaxis with Enoxaparin Reduces Mortality in Patients Hospitalized with COVID-19
Severe acute respiratory syndrome caused by COVID-19 is associated with a hypercoagulable state and an increased risk of thrombotic events. Since the beginning of the pandemic, thromboprophylaxis has been recommended for these patients despite initial insufficient evidence. In the fall of 2020, an observational study was published confirming the beneficial effect of enoxaparin on reducing mortality and the risk of ICU admission in patients with severe COVID-19.
News Benefit of ixazomib in patients with relapsed/refractory multiple myeloma in routine clinical practice
The results of treating relapsed or refractory multiple myeloma in real-world routine clinical practice were published by a broad team of Czech experts in the journal BMC Cancer.
News Is Baricitinib Suitable for Long-Term Treatment of Rheumatoid Arthritis?
The nature of rheumatoid arthritis requires effective and long-term treatment. The current analysis of data from the long-term extension RA-BEYOND reveals the potential of baricitinib in maintaining low disease activity and remission with long-term use.