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News Traveling with MS –⁠ Is Vaccination a Limitation?

What about the need for vaccination when traveling abroad? Which vaccines should you be cautious about? And how to time vaccination concerning disease activity and the individual medications used in multiple sclerosis (MS) therapy?

Source: Multiple Sclerosis 5. 6. 2023

News To what extent can the actual level of ALP, ALT, or bilirubin differ from the measured value?

A physician who bases clinical decisions on laboratory-determined values of biological parameters or their changes should always consider the possible measurement deviation, which for alkaline phosphatase (ALP), alanine aminotransferase (ALT), or bilirubin can reach several percent in both positive and negative directions.

Source: Primary Biliary Cholangitis 14. 5. 2021

News How to Detect COPD Early in Primary Care?

Chronic obstructive pulmonary disease (COPD) can be present even in individuals without obvious subjective symptoms, or the emerging symptoms may be overlooked by both the patient and the doctor due to their very gradual development. So, what is the path to early detection of COPD in primary care, and how can this disease be distinguished from others accompanied by similar manifestations?

Source: Treatment of Asthma and COPD 6. 4. 2022

News Indication of Bilastine in Specific Patient Groups −⁠ Practical Tips for Clinical Practice

Bilastine is a non-sedating H1-antihistamine, which is very well tolerated by patients. It can be indicated in the therapy of allergic diseases in both pediatric and adult populations. What are the possibilities of its use in specific patient groups?

Source: Allergic Reactions 24. 5. 2022

Články časopisu Fatal meningococcal sepsis caused by Neisseria meningitidis serogroup W

Author of the article: L. Krbková, M. Fedora, J. Pavelka, P. Křížová, K. Labská, Z. Vacková Source: Česko-slovenská pediatrie | 5/2017 9. 10. 2017

News Inosine Pranobex in the Treatment of Cervical HPV Infections

The aim of the review article published in the journal Infection and Drug Resistance was to evaluate the available data on the potential use of inosine pranobex in the treatment of patients with a positive human papillomavirus finding in a cervical smear.

Source: Viral infections 13. 7. 2022

News How to Save a Leg from Amputation?

Feared complications in diabetics include defects in typical locations on the lower limbs. Their presence and frequent recurrences increase the risk of possible amputation of varying degrees, mainly depending on the involvement of deep structures, i.e., tendons, joint capsules, joints, and bones. How can this scenario be avoided? One answer might be HydroTherapy.

Source: Wound Healing 10. 8. 2022

News Idiopathic Pulmonary Fibrosis: Rare Disease with Severe Prognosis

Idiopathic pulmonary fibrosis (IPF) represents a diagnostic and therapeutic challenge. This rare diffuse primary fibroproliferative involvement of lung tissue is characterized by progressive exertional dyspnea, with antifibrotic treatment being the first-line therapeutic modality.

Source: Pulmonary Fibrosis 14. 4. 2020

Články časopisu Can affecting of subchondral bone slow the progression of osteoarthritis?

Author of the article: Pavelka Karel Source: Clinical Osteology | 2/2019 2. 9. 2019

News When to Consider Gaucher Disease and How to Diagnose It Early and Correctly

Considering Gaucher disease (GD) as a cause of a patient's problems, especially in the case of splenomegaly and bleeding manifestations, is very important, regardless of age. Screening using the dry blood spot method is available and very simple.

Source: Rare Diseases in Hematology 16. 5. 2023

News Polatuzumab Vedotin in the Treatment of NHL -⁠ News from the 25th EHA Congress

Polatuzumab vedotin (Polivy) is approved in the EU for the treatment of patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), for whom hematopoietic stem cell transplantation (HSCT) is not suitable. We provide an overview of the latest news regarding the role of this modern medicine in the therapy of non-Hodgkin's lymphomas (NHL), presented at the 25th Congress of the European Hematology Association (EHA), held virtually due to the pandemic situation.

Source: Non-Hodgkin Lymphomas and CLL 29. 9. 2020

News Domestic application of biological asthma treatment improves quality of life and reduces doctor visits

The benefits of the possibility of home application of omalizumab, a monoclonal antibody indicated for patients with severe allergic asthma, are summarized by Dr. Jakub Novosad, Ph.D., from the Institute of Clinical Immunology and Allergology, Charles University Medical Faculty and University Hospital Hradec Králové.

Source: Asthma under control 9. 4. 2020

Články časopisu Obesity and its influence on sexual dysfunctions

Author of the article: Dita Pichlerová, Jitka Herlesová, Petr Weiss Source: Praktická gynekologie | 2/2013 1. 5. 2013

News Alternative to benzodiazepines or clomethiazole in the treatment of alcohol withdrawal syndrome?

Alcohol withdrawal syndrome (AWS) is a potentially life-threatening condition. A meta-analysis published in the journal Pharmacopsychiatry in September 2019 examines the effect of the combination of tiapridal and carbamazepine in the treatment of AWS. Is this combination a viable alternative to benzodiazepines or clomethiazole?

Source: Geriatric Patient 20. 3. 2020

News Levodropropizine –⁠ a non-codeine antitussive with minimal side effects, contraindications, and drug interactions

For symptomatic treatment of dry, irritating, and exhausting cough, both codeine and non-codeine antitussives can be used. One of the non-codeine antitussives is levodropropizine. Its antitussive effect is comparable to centrally acting codeine antitussives, but with a significantly lower incidence of side effects. Compared to codeine, it has a much narrower range of contraindications, and no interactions with benzodiazepines or drugs used in the treatment of bronchopulmonary diseases have been observed.

Source: Cough Therapy 10. 1. 2022