Pharmacotherapy in LUTS/BPH in everyday clinical practise. How to choose the optimal alternative?

Authors: M. Ghazal
Published in: Urol List 2013; 11(2): 12-24


Benign hyperplasia of the prostate (BPH) is the most common non-malignant male disease that can be managed by non invasive procedures. The incidence is not evident due to the existence of different forms of this disease (histological, asymptomatic – compensated obstruction, symptomatic for example subvesical obstruction). It is generally acceptable, that nearly 40 % of men in their forties are affected by some lower urinary tract symptoms. Because there are additional diseases of both sexes that can cause identical symptoms the term lower urinary tract symptoms (LUTS) was introduced. In case of prostate obstruction accurate terminology is LUTS/BPH (Coffey). Diagnostic workup is quite undemanding, however differential diagnosis is unbelievably broad. It is true that basic examination includes digital rectal examination, appropriate diagnosis (including a specific questionnaire IPSS) and urine analysis to rule out infection. Prostate specific antigen (PSA) level is important in patients perspective for a therapy of possibly diagnosed prostate cancer. The examination of urinary flow by means of uroflowmetry (UFM) having in mind the limits of urine volume and data as such.

Key words:
benign prostatic hyperplasia, lower urinary tract symptoms, pharmacotherapy


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