Total duodenopancreatectomy for renal cell carcinoma metastases – case report

Authors: R. Donát;  M. Sabol;  Š. Durdík
Authors‘ workplace: Klinika onkologickej chirurgie LF Univerzity Komenského a Onkologický Ústav sv. Alžbety, Bratislava prednosta: prof. MUDr. Š. Durdík, PhD., MHA
Published in: Rozhl. Chir., 2016, roč. 95, č. 2, s. 87-90.
Category: Case Reports


The frequency of pancreatic metastases ranges from 2% to 5%. Pancreas is an elective site for metastases from renal carcinoma. Pancreatic metastases from renal cell carcinoma are frequently the only metastatic site and they typically occur in the seventh decade of life.

Case report:
We report 1 female patient (aged 58 years) with multifocal and isolated pancreatic metastases of renal cell carcinoma. Total duodenopancreatectomy was performed.

In selected cases, pancreatic resection due to renal cell cancer metastases is deemed indicated, improving overall patient survival.

Key words:
renal cell carcinoma (RCC) − isolated pancreatic metastases − total duodenopancreatectomy


1. Zerbi A, Ortolano E, Balzano G, et al. Pancreatic metastasis from renal cell carcinoma: which patients benefit from surgical resection? Ann Surg Oncol 2008;15:1161−8.

2. Sellner F, Tykalsky N, De Santis M, et al. Solitary and multiple isolated metastases of clear cell renal carcinoma to the pancreas: an indication for pancreatic surgery. Ann Surg Oncol 2006;13:75−85.

3. Law CH, Wei AC, Hanna SS, et al. Pancreatic resection for metastatic renal cell carcinoma: presentation, treatment, and outcome. Ann Surg Oncol 2003;10:922−6.

4. Béchade D, Palazzo L, Desramé J, et al. Pancreatic metastasis of renal cell carcinoma: report of three cases. Rev Med Interne 2002;23:862−6.

5. Loveček M, Skalický P, Kliment M, et al. Metastázy do pankreatu-diagnostika a možnosti radikální léčby, komplikace, přežívání. Rozhl Chir 2015,94:193−8.

6. Crippa S, Angelini C, Mussi C, et al. Surgical treatment of metastatic tumors to the pancreas: a single center experience and review of the literature. World J Surg 2006;30:1536–42.

7. Konstantinidis IT, Dursun A, Zheng H, et al. Metastatic tumors in the pancreas in the modern era. J Am Coll Surg 2010;211:749–53.

8. Wente MN, Kleeff J, Esposito I, et al. Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature. Pancreas 2005;30:218–22.

9. Masetti M, Zanini N, Martuzzi F, et al. Analysis of prognostic factors in metastatic tumors of the pancreas: a single-center experience and review of the literature. Pancreas 2010;39:135−43.

10. Bahra M, Jacob D, Langrehr JM, et al. Metastatic lesions to the pancreas. When is resection reasonable? Chirurg 2008;79:241–8.

11. Varker KA, Muscarella P, Wall K, et al. Pancreatectomy for non-pancreatic malignancies results in improved survival after R0 resection. World J Surg Oncol 2007;5:145

12. Reddy S, Edil BH, Cameron JL, et al. Pancreatic resection of isolated metastases from nonpancreatic primary cancers. Ann Surg Oncol 2008;15:3199−206.

13. Santoni M, Conti A, Partelli S, et al. Surgical resection does not improve survival in patients with renal metastases to the pancreas in the era of tyrosine kinase inhibitors. Ann Surg Oncol 2015;22:2094−100.

14. Ballarin R, Spaggiari M, Cautero N, et al. Pancreatic metastases from renal cell carcinoma:The state of the art. World J Gastroenterol 2011:1:4747−56.

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