Hepatolithiasis – A Rare Disorder in Our Population

Authors: V. Třeška ;  T. Skalický ;  A. Sutnar ;  J. Kuntscherová *
Authors‘ workplace: Chirurgická klinika FN v Plzni, přednosta: prof. MUDr. Vladislav Třeška, DrSc. ;  Šiklův patologicko-anatomický ústav, přednosta: prof. MUDr. Michal Michal, Ph. D. *
Published in: Rozhl. Chir., 2009, roč. 88, č. 3, s. 115-118.
Category: Monothematic special - Original


The authors describe diagnostic and therapeutic options of hepatolithiasis, which is a rare disorder in our population.

The authors present 3 case- reviews of patients operated for hepatolithiasis in the Plzeň Faculty Hospital Surgical Clinic during 2000–2008. In a single subject, the finding was related to a Caroli syndrome. All subjects suffered from symptomatic hepatolithiases (abdominal pains, cholangiogenic sepsis), which was complicated by advanced liver cirrhosis in one case. The diagnostic measures included ultrasonography, computer tomography, MRI cholangiography and endoscopic retrograde cholangiography. In all the subjects, left-sided lobectomy was performed for findings located in the liver segments 2 and 3.

The 30-day postoperative mortality was nil. In a single female patient, liver resection (segment 4) was performed for segmental bile duct dilation, bile fistule and chilangiogenic sepsis.

Resection of the affected liver region is the method of choice in the management of hepatolithiasis.

Key words:
hepatolithiasis – diagnostics – treatment


1. Huang, M. H., Chen, Ch., Yen, C. M., Yang, J. C., Yang, C. C., Yeh, Y. H., Chou, D. A., Yueh, S. K., Yang, Y. Y., Nien, C. K. Relation of hepatolithiasis to helminthic infestation. J. Gastroenterolog. Hepatol., 2005, č. 20, s. 141–146.

2. Mori, T., Sugiyama, M., Atomi, Y. Gallstone disease: Management of intrahepatic stones. Best Pract. Res. Clin. Gastroenterol., 2006, č. 20, s. 1, s. 1117–1137.

3. Lee, C. C, Wu, C. Y., Chen, A. G. What is the impal of koexistence of hepatolithiasis on cholangiocarcinoma? J. Gastroenterol. Hepatol., 2002, č. 17, s. 1015–1020.

4. Kamiya, J., Kitagawa, Y., Nimura, Y. Intrahepatic stones. In: L. H. Blumgart, Surgery of the liver, biliary tract and pancreas. Saunders Elsevier, Philadelphia, 2006, s. 586–596.

5. Sakai, Y., Tsuyuguchi, T., Yukisawa, S., Tsuchiya, S., Sugiyama, H., Miyakawa, K., Fukuda, Y., Ebara, M., Nonaka, H., Ikehira, H., Obata, T., Miyazaki, M., Yokosuka, O. A new approach for diagnosis of hepatolithiasis: magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administrativ in the evaluation of hepatolithiasis. Hepatogastroenterology, 2008, č. 55, s. 1801–1805.

6. Huang, M. H., Chen, Ch., Yang, J. C, Yeh, Y. H., Chou, D. A., Mo, L. R., Yueh, S. K., Nien, C. K. Long-term outcome of percutaneous transhepatic cholangioscopic lithotomy for hepatolithiasis. Am. J. Gastroenterol., 2003, č. 98, s. 2589–2590.

7. Chen, Ch., Huang, M. H., Yang, J. C., Yang, C. C., Yeh, Y. H., Mo, L. R., Wu, H. S., Chou, D. A., Yueh, S. K., Nieh, C. K. The treatment of isolated left-sided hepatolithiasis. Hepatogastroenterology, 2008, č. 55, s. 600–604.

8. Huang, Z. Q., Huang, X. Q., Zhang, W. Z., Xu, L. N., Yang, T., Zhang, A. Q., Dong, J. H. Liver resection in hepatolithiasis: 20-year’s evolution. Zhonqhua Wai Ke Za Zhi, 2008, č. 46, s. 1450–1452.

9. Chen, Z. Y., Yan, L. N., Zeng, Y., Wen, T. F., Li, B., Zhao, J. C., Wang, W. T., Yang, J. Y., Xu, M. Q., Ma, Y. K., Wu, H. Preliminary indication for liver transplantation for hepatolithiasis. Transplant. Proc., 2008, č. 40, s. 3517–3522.

10. Feng, Z. Q., Huang, Z. Q., Xu, L. N., Liu, R., Zhang, A. Q., Huang, X. Q., Zhang, W. Z., Dong, J. H. Liver resection for benign hepatic lesions: A retrospective analysis of 827 consecutive cases. World J. Gastroenterol., 2008, č. 14, s. 7247–7251.

11. Chen, D. W., Tung-Ping Poon, R., Liu, C. L., Fan, S. T., Wong, J. Immediate and long-term outcomes of hepatectomy for hepatolithiasis. Surgery, 2004, č. 135, s. 386–393.

12. Marín, C., Robles, R., Pastor, P., Parrilla, P. Liver resection in the treatment of intrahepatic lithiasis.Immediate and long-term results in a single-center series. Rev. Esp. Enferm. Dig., 2008, č. 100, s. 225–229.

13. di Carlo, I., Sauvanet, A., Belghiti, J. Intrahepatic lithiasis: a Western experience. Surg. Today, 2000, č. 30, s. 319–322.

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