New Therapeutic Procedures in Otolaryngology Using Mesenchymal Stromal Cells
Authors:
L. Školoudík 1; Viktor Chrobok 1; D. Kalfeřt 1; Z. Kočí 2,3,4; E. Syková 2,3; S. Filip 5
Authors‘ workplace:
Klinika otorinolaryngologie a chirurgie hlavy a krku, Fakultní nemocnice Hradec Králové, Univerzita Karlova v Praze, Lékařská fakulta v Hradci Králové
1; Ústav experimentální medicíny Akademie věd České republiky, v. v. i.
2; Oddělení neurověd, 2. lékařská fakulta Univerzity Karlovy v Praze
3; Bioinova, s. r. o., Praha
4; Klinika onkologie a radioterapie, Fakultní nemocnice Hradec Králové, Univerzita Karlova v Praze, Lékařská fakulta v Hradci Králové
5
Published in:
Otorinolaryngol Foniatr, 65, 2016, No. 2, pp. 97-101.
Category:
Review Article
Overview
Multipotent mesenchymal stromal cells (MSC) are used for regeneration of injured mesenchymal tissue due to their self-renewal capacity and ability to differentiate into cells of mesenchymal tissue (bone, cartilage, muscle, fat, nerve or fibrous tissues). They regenerate various tissues through self-renewal, differentiation capacity, immune modulation and secretion of bioactive molecules. Authors present a review of MSC applications in otorhinolaryngology. The major interest is focused on phonosurgery, sensorineural deafness and reconstruction of large tissue defects with bone, cartilage or soft tissue replacement. The MSCs research in Czech otorhinolaryngology is focused on bone tissue replacement. Current point of interest is the temporal bone and treatment of bone defects after middle ear surgery.
KEYWORDS:
mesenchymal stromal cells, bone replacement, middle ear surgery
Sources
1. Aggarwal, S., Pittenger, M. F.: Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood, 205, 2005, s. 1815-1822.
2. Bas, E., Van De Water, T. R., Lumbreras, V. et al.: Adult human nasal mesenchymal-like stem cells restore cochlear spiral ganglion neurons after experimental lesion. Stem Cells Dev., 23, 2014, s. 502-514.
3. Go, T., Jungebluth, P., Baiguero, S. et al.: Both epithelial cells and mesenchymal stem cell-derived chondrocytes contribute to the survival of tissue-engineered airway transplants in pigs. J. Thorac. Cardiovasc. Surg., 139, 2010, s. 437-443.
4. Halum, S. L., Hiatt, K. K., Naidu, M. et al.: Optimization of autologous muscle stem cell survival in the denervated hemilarynx. Laryngoscope, 118, 2008, s. 1308-1312.
5. Hanson, S. E., Bentz, M. L., Hematti, P.: Mesenchymal stem cell therapy for nonhealing cutaneous wounds. Plast. Reconstr. Surg., 125, 2010, s. 510-516.
6. Hertegard, S., Cedervall, J., Svensson, B. et al.: Viscoelastic and histologic properties in scarred rabbit vocal folds after mesenchymal stem cell injection. Laryngoskope, 116, 2006, s. 1248-1254.
7. Hilfiker, A., Kasper, C., Hass, R. et al.: Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation?, Langenbecks Arch. Surg., 396, 2011, s. 489-497.
8. Chen, X., Thibeault, S. L. et al.: Biocompatibility of a synthetic extracellular matrix on immortalized vocal fold fibroblasts in 3-D culture. Acta Biomater., 6, 2010, s. 2940-2948.
9. Jeon, S. J., Oshima, K., Heller, S. et al.: Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells. Mol. Cell Neurosci., 34, 2007, s. 59-68.
10. Johnson, B. Q., Fox, R., Chen, X. et al.: Tissue regeneration of the vocal fold using bone marrow mesenchymal stem cells and synthetic extracellular matrix injections in rats. Laryngoscope, 120, 2010, s. 537-545.
11. Kasagi, H., Kuhara, T., Okada, H. et al.: Mesenchymal stem cell transplantation to the mouse cochlea as a treatment for childhood sensorineural hearing loss. Int. J. Pediatr. Otorhinolaryngol., 77, 2013, s. 936-942.
12. King, S. N., Hanson, S. E., Hematti, P. et al.: Current applications of mesenchymal stem cells for tissue replacement in otolaryngology-head and neck surgery. Am. J. Stem Cells, 30, 2012, s. 225-238.
13. Kon, E., Muraglia, A., Cosi, A. et al.: Autologous bone marrow stroma cells loaded onot porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones, J. Biomed. Mat. Res., 49, 2000, s. 328-337.
14. Lataillade, J. J., Doucet, C., Bey, E. et al.: New approach to radiation burn treatment by dosimetry-guided surgery combined with autologous mesenchymal stem cell therapy. Regen. Med., 2, 2007, s. 785-794.
15. Lin, G., Liu, G., Banie, L. et al.: Tissue distribution of mesenchymal stem cell marker Stro-1, Stem Cells Dev., 20, 2011, s. 1747-1752.
16. Long, J. L., Neubauer, J., Zhang, Z. et al.: Functional testing of a tissueengineered vocal fold cover replacement. Otolaryngol. Head Neck Surg., 142, 2010, s. 438-440.
17. Long, J. L., Zuk, P., Berke, G. S. et al.: Epithelial differentiation of adipose-derived stem cells for laryngeal tissue engineering. Laryngoskope, 120, 2010, s. 125-131.
18. Majore, I., Moretti, P., Stahl, F. et al.: Growth and differentiation properties of mesenchymal stromal cell populations derived from whole human umbilical cord, Stem Cell Rev. Rep., 7, 2011, s. 17-31.
19. Matsumoto, D., Sato, K., Gonda, K. et al.: Cell-assisted lipotransfer: Supportive use of human adiposederived cells for soft tissue augmentation with lipoinjection. Tissue Eng, 12, 2006, s. 3375-3382.
20. Matsuoka, A. J., Kondo, T., Miyamoto, R. T. et al.: Enhanced survival of bone-marrow-derived pluripotent stem cells in an animal model of auditory neuropathy. Laryngoscope, 117, 2007, s. 1629-1635.
21. Méndez-Ferrer, S., Michurina, T. V., Ferraro, F. et al.: Mesenchymal and haematopoietic stem cells form a unique bone marrow niche, Nature, 466, 2010, s. 829-834.
22. Mobasheri, A., Csaki, C., Clutterbuck, A. L. et al.: Mesenchymal stem cells in connective tissue engineering and regenerative medicine: applications in cartilage repair and osteoarthritis therapy, Histol. Histopathol., 24, 2009, s. 347-366.
23. Naito, H., Tojo, T., Kimura, M. et al.: Engineering bioartificial tracheal tissue using hybrid fibroblast-mesenchymal stem cell cultures in collagen hydrogels. Interact. Cardiovasc. Thorac Surg., 12, 2011, s. 156-161.
24. Park, H., Karajanagi, S., Wolak, K. et al.: Three-dimensional hydrogel model using adipose-derived stem cells for vocal fold augmentation. Tissue Eng. Part A, 16, 2010, s. 535-543.
25. Peng, L., Jia, Z., Yin, X. et al.: Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue, Stem Cells Dev., 17, 2008, s. 761-773.
26. Peng, H., Ming, L., Yang, R. et al.: The use of laryngeal mucosa mesenchymal stem cells for the repair the vocal fold injury. Biomaterials, 34, 2013, s. 9026-9035.
27. Phinney, D. G., Prockop, D. J.: Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair--current views. Stem Cells, 25, 2007, s. 2896-2902.
28. Prockop, D. J., Oh, J. Y.: Mesenchymal stem stromal cells (MSCs): Role as guardians of inflammation. Mol. Ther., 20, 2012, s. 14-20.
29. Qian, H., Le Blanc, K., Sigvardsson, M. et al.: Primary mesenchymal Stem and progenitor cells from bone marrow lack expression of CD44 protein. J. Biol. Chem., 287, 2012, s. 25795-25807.
30. Skoloudik, L., Chrobok, V., Kalfert, D. et al.: Multipotent mesenchymal stromal cells in otorhinolaryngology. Med. Hypotheses, 82, 2014, s. 769-773.
31. Skoloudik, L., Chrobok, V., Kalfert, D. et al.: Human multipotent mesenchymal stromal 4. cells in the treatment of postoperative temporal bone defect: an animal model. Cell Transplant., oct 22, 2015, PubMed PMID: 26497735
32. Suzuki, T., Kobayashi, K., Tada, Y. et al.: Regeneration of the trachea using a bioengineered scaffold with adipose-derived stem cells. Ann. Otol. Rhinol. Laryngol, 117, 2008, s. 453-463.
33. Svensson, B., Nagubothu, R. S., Cedervall, J. et al.: Injection of human mesenchymal stem cells improves healing of scarred vocal folds: Analysis using a xenograft model. Laryngoscope, 120, 2010, s. 1370-1375.
34. Viateau, V., Guillemin, G., Bousson, V. et al.: Long-bone critical-size defects treated with tissue-engineered grafts: A study on Wheel. J. Orthop. Res., 25, 2007, s. 741-749.
35. Warren, S., Nacamuli, R. K., Song, H. J. et al.: Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold. J. Craniofac. Surg., 15, 2004, s. 34-37.
Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
2016 Issue 2
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