Mucosal Pemphigoid – Diagnostic Obstacles

Czech version

Authors: Jana Krtičková ¹; V. Radochová ²; D. Hadži Nikolov ³; Z. Dufek ¹; Jana Šatanková ¹
Authors‘ workplace: Klinika otorinolaryngologie a chirurgie hlavy a krku, Fakultní nemocnice Hradec Králové, Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. V. Chrobok, CSc., Ph. D. ¹; Stomatologická klinika, Fakultní nemocnice Hradec Králové, Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta doc. MUDr. R. Slezák, CSc. ²; Fingerlandův ústav patologie, Fakultní nemocnice Hradec Králové, Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. A. Ryška, Ph. D. ³
Published in: Otorinolaryngol Foniatr, 63, 2014, No. 4, pp. 239-242.
Category: Case History

Overview

Pemphigoid belongs to a group of autoimmune diseases, characterised by the presence of autoantibodies against structural components of the dermal-epidermal junction, with the formation of subepithelial blisters. Clinical manifestation is very variable and can be associated with diagnostic delay. We report a case of 83years-old female with oral mucosa involvement in mucous membrane pemphigoid and review of the current literature. This case report emphasizes the importance of direct immunofluorescence as a diagnostic tool.

Keywords:
bullous pemphigoid, mucous membrane pemphigoid, oral cavity, immunofluorescency

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Article was published in

Otorhinolaryngology and Phoniatrics

2014 Issue 4