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Significance of radiosurgery in the treatment of brain metastases


Authors: Gabriela Šimonová;  Roman Liščák
Authors‘ workplace: Oddělení stereotaktické a radiační neurochirurgie Nemocnice Na Homolce, Praha
Published in: Čas. Lék. čes. 2011; 150: 273-277
Category: Review Article

Overview

Brain metastases are diagnosed in about 30% adult patients with generalized carcinomas, their accompanying severe neurological symptoms cause worsening quality of patient’s life. The development of magnetic resonance imaging and stereotactically guided radiosurgery and radiotherapy enable to apply relatively high doses to well defined intracranial target volumes. Progression free survival after irradiation of brain lesions depends on several prognostic factors. Radiosurgery using gamma knife is an effective treatment with low rate of postradiation complications.

Key words:
brain metastases, progression free survival, tumor response, prognostic factors.


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