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Measurement of exhaled nitric oxide in the diagnosis of asthma


Authors: Petr Čáp
Authors‘ workplace: Centrum alergologie a klinické imunologie Nemocnice Na Homolce, Praha
Published in: Čas. Lék. čes. 2011; 150: 297-298
Category: Special Articles

Overview

Currently exhaled nitric oxide is taken for the best inflammatory marker used in diagnosis of asthma. This short communication deals with recent recommendation, our own experience and comments on the importance of exhaled nitric oxide in clinical practise.

Key words:
nitric oxide, asthma, inflammation.


Sources

1. Čáp P, Brezina M. Neinvazivní vyšetřování zánětu u astmatu u dětí a dospělých. Praha: Mladá fronta 2009.

2. Shaw DE, Wilson E, Pavord ID. Exhaled nitric oxide in asthma. In: Horvath I, Jongste J. Exhaled biomarkers. European Respiratory Monograph. Sheffield 2010; 32–44.

3. Consensus Statement on the Use of Fractional Exhaled Nitric Oxide (FENO) in the Cinical Management of astma. National JewishHealth, December 2009, Denver; http://www.njhealth.org.

4. Votruba J, Čáp P. Vydechovaný oxid dusnatý a jeho korelace s bioptickými nálezy u pacientů s chronickým kašlem. Čas Lék čes 2009; 148: 429–433.

5. Čáp P, Malý M, Pehal F, Pelikan Z. Exhaled leukotrienes and bronchial responsiveness to methacholine in patients with seasonal allergic rhinitis. Ann Allergy Asthma Immunol 2009; 102: 103–109.

6. Taylor DR, Pijnenburg MW, Smith AD, De Jongste JC. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 2006; 61: 817–827.

7. Schleich FN, Seidel L, Sele J, Manise M, Quaedvlieg V, Michils A, Louis R. Exhaled nitric oxide thresholds associated with a sputum eosinophil count > 3% in a cohort of unselected patients with asthma. Thorax 2010; 65: 1039–1044.

8. Smith AD, Cowan JO, Brassett KP, et al. Exhaled nitric oxide: a predictor of steroid response.Am J Respir Crit Care Med 2005; 172: 453–459.

9. Chládkova J, Krčmova I, Chládek J, Čáp P, Micuda S, Hanzálkova Y. Validation of nitrite and nitrate measurements in exhaled breath condensate. Respiration 2006; 73: 173–179.

10. Čáp P, Dryahina K, Pehal F, Španěl P. Selected ion flow tube mass spectrometry of exhaled breath condensate headspace. 2008; 22: 2844–2850.

Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management

Article was published in

Journal of Czech Physicians

Issue 4-5

2011 Issue 4-5

Most read in this issue
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