Insulin Action in Polycystic Ovary Syndrome
Authors:
G. †šindelka; J. Škrha; D. Cibula 1; M. Prázný
Authors‘ workplace:
III. interní klinika 1. LF UK a VFN, Praha 1Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha
Published in:
Čas. Lék. čes. 2002; : 769-772
Category:
Overview
Background.
Polycystic ovary syndrome (PCOS) has been accompanied by insulin resistance. The aim of thisstudy was to compare the insulin action between thin and obese women with PCOS and to analyse its relationshipto serum concentration of selected hormones.Methods and Results. Total number of 32 women with PCOS between them there were 22 thin and 10 obesesubjects was examined in this study. Control group consisted of 21 nonobese healthy women. The insulin action wasdetermined by euglycemic hyperinsulinemic clamp. Normal insulin action found in the group of thin women withPCOS was comparable with that in healthy controls whereas insulin resistance was observed in obese ones. Aninverse relationship was found between insulin action and body mass index (r=0.62, p
Key words:
polycystic ovary syndrome, insulin action, euglycemic clamp.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain managementArticle was published in
Journal of Czech Physicians
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