Kidney, Aging and Transplantation
Authors:
O. Viklický; R. Böhmová; U. W. Heemann 1
Authors‘ workplace:
Klinika nefrologie a Oddělení klinické imunologie Transplantačního centra IKEM, Praha 1Universitätsklinikum, Essen, SRN
Published in:
Čas. Lék. čes. 2002; : 765-768
Category:
Overview
The discrepancy between the increasing number of patients listed for kidney transplantation and limited cadaverdonor sources has led the transplant community towards indication of elderly people as potential kidney donors.Based on clinical data, the kidney grafts explanted from aged donors have limited survival rates compared withyounger ones. The donor age has been also implicated as the important alloantigen-independent risk factor for lateronset of chronic allograft neprohopathy called chronic rejection. In this review we focused on some pathophysiologicalaspects of kidney aging and on the fate of transplanted kidney removed from elderly donors.
Key words:
aging, kidney transplantation, chronic rejection.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain managementArticle was published in
Journal of Czech Physicians
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