Authors: M. Bednář; P. Bezdíček 1 Authors‘ workplace: Ústav lékařské mikrobiologie 3. LF UK a FNKV, Praha, 1 Division of Pulmonary and Critical Care Medicine, The New York Hospital - Cornell University Medical College, New York, USA Published in: Čas. Lék. čes. 1999; : 82-84 Category:
Currently, talc is the most effective and widely-used agent for chemical pleurodesis in the treatment of bothmalignant pleural effusion and pneumothorax. Its popularity has been growing due to the low incidence of sideeffects, low cost and higher success rate in comparison with other agents (tetracyclines, bleomycin, Corynebacteriumparvum). The guidelines for talc pleurodesis are summarized and the history of the Corynebacterium parvum as anagent for chemical pleurodesis is mentioned. Its production in the Czech Republic has been halted due to the increasedinterest in the talc as a chemical sclerosant.
Key words: malignant effusion, pneumothorax, pleurodesis, talc, Corynebacterium parvum, tetracyclin, bleomy-cin.
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