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Hypersensitive reaction after application of heparin with activation heparin induced trombocytopenia in initiation of intermittent haemodialysis
Authors: Jan Masopust; Jiří Charvát; Dana Mokrá; Ondřej Hloch; Jan Háša
Authors‘ workplace: Interní klinika 2. LF UK a FN Motol Praha, přednosta prof. MUDr. Milan Kvapil, CSc., MBA
Published in: Vnitř Lék 2015; 61(3): 259-262
Category: Case Report
Overview
Our report describes the case of patient with hypersensitive reaction regularly arising early after initiation of haemodialysis. This characteristic reaction with pletoric face coloration, bronchospasm, increase of blood pressure, anxiety and decrease of blood oxygen saturation at the consequence and central cyanosis was regularly present without dependence on type of dialysis membrane, drug premedication or prophylactic flushing haemodialysis system by isotonic natrium chloride solution. Low platelet value and trouble-free haemodialysis realized without heparin showed real cause of patients problem. Resolution of this state was regional citrate anticoagulation during intermitent haemodialysis.
Key words:
haemodialysis – heparin induced trombocytopenia – hypersensitive reaction – regional anticoagulation
Sources
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4. Crowther MA, Cook DJ, Albert M et al. The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patiens. J Crit Care 2010; 25(2): 287–293.
5. Králová S, Klodová D, Gumulec J. Heparinem indukovaná trombocytopenie. Vnitř Lék 2006; 52(Suppl 1): 98–106.
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Labels
Diabetology Endocrinology Internal medicine
Article was published inInternal Medicine
2015 Issue 3-
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