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New knowledge in the heredity of autoimmune diabetes.
1st part – Monogenetically determined types of autoimmune diabetes


Authors: J. Vavřinec;  J. Vosáhlo
Authors‘ workplace: Klinika dětí a dorostu 3. lékařské fakulty UK a FN Královské Vinohrady, Praha, přednosta doc. MUDr. Felix Votava, Ph. D.
Published in: Vnitř Lék 2007; 53(6): 694-701
Category: Reviews

Předneseno na Diabetologickém dnu 23. listopadu 2006 ve Zlíně k příležitosti významného životního jubilea prof. MUDr. Jaroslava Rybky, DrSc.

Overview

The incidence of type 1 diabetes (DM1) varies greatly among different nations and ethnic groups. Precise mapping of DM1 incidence and its trends is useful in the study of the interaction of genetic and non-genetic factors which influence the manifestation and course of the disease. Important progress has been made in the understanding of the mechanisms of autoimmune diabetes by the study of genes and autoimmune forms of monogenetic diabetes.

Key words:
monogenetic autoimmune diabetes mellitus – heredity – APS-I + II – IPEX


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Diabetology Endocrinology Internal medicine

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