#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Extramedullary plasmacytoma of the thyroid gland – a rare vause of a solitary struma nodosa and hyperthyroidism


Authors: D. Karásek 1;  M. Halenka 1;  L. Kučerová 2;  M. Kamínek 3;  Z. Fryšák 1;  V. Ščudla 1
Authors‘ workplace: III. interní klinika Lékařské fakulty UP a FN, Olomouc, přednosta prof. MUDr. Vlastimil Ščudla, CSc. 1;  Ústav patologie Lékařské fakulty UP a FN, Olomouc, přednosta prof. MUDr. Zdeněk Kolář, CSc. 2;  Klinika nukleární medicíny Lékařské fakulty UP a FN, Olomouc, přednosta doc. MUDr. Miroslav Mysliveček, Ph. D. 3
Published in: Vnitř Lék 2005; 51(1): 97-100
Category: Case Reports

Overview

Authors describe an abnormal case of a secondary thyroid gland damage caused by extramedullary plasmacytoma manifesting as a solitary thyroid gland nodule and hyperthyroidism. During chemotherapy treatment a remission of a primary disorder has been reached – multiple myeloma, total disappearance of the nodule, and normal thyroid function. The article proves the importance of an ultrasonic examination of the thyroid gland accompanied by a fine needle aspiration biopsy.

Key words:
extramedullary plasmacytoma – thyroid gland – fine needle aspiration biopsy


Sources

1. Adam Z, Králová E. Solitární plazmocytom. In: Adam Z, Hájek R, Mayer J et al. Mnohočetný myelom a další monoklonální gamapatie. Brno: Masarykova univerzita 1999: 37–38.

2. Batsakis JG, Fries GT, Goldman RT et al. Upper respiratory tract plasmacytoma. Arch Otolaryngol 1964; 79: 613–618.

3. Belfiore A. The use of fine needle aspiration biopsy (FNAB) in thyroid disease. Thyroid international 2002; 2: 1–17.

4. Bourtsos EP, Bedrossian CWM, de Frias DVS et al. Thyroid plasmacytoma mimicking medullary carcinoma: a potential pitfall in aspiration cytology. Diagn Cytopathol 2000; 23: 354–358.

5. Čáp J, Ryška A. Aspirační cytologie štítné žlázy. Hradec Králové: Nucleus 2003.

6. Doria R, Jekel JF, Cooper DL. Thyroid lymphoma. The case for combined modality therapy. Cancer 1994; 73: 200–206.

7. Hardoff R, Bar-Shalom R, Dharan M et al. Hodgkin’s disease presenting as a solitary thyroid nodule. Clin Nucl Med 1995; 20: 37–41.

8. Hazard JB, Schildecker WW. Plasmacytoma of the thyroid. Am J Pathol 1949; 25: 819–820.

9. Holm LE, Blomgren H, Löwhagen T. Cancer risks in patients with chronic lymphocytic thyroiditis. N Engl J Med 1985; 312: 601–604.

10. Kapadia SB, Desai U, Cheng VS. Extramedullary plasmacytoma of the head and neck: a clinicopathological study of 20 cases. Medicine (Baltimore) 1982; 61: 317–329.

11. Kovacs CS, Mant MJ, Nguyen GK et al. Plasma cell lesions of the thyroid: report of a case of solitary plasmacytoma and a review of the literature. Thyroid 1994; 4: 65–71.

12. MacPherson TA, Dekker A, Kapadia SB. Thyroid gland plasma cell neoplasm (plasmacytoma). Arch Pathol Lab Med 1981; 105: 570–572.

13. Malpas JS, Bergsagel DE, Kyle RA. Myeloma-biology and management. New York: Oxford University Press 1995.

14. Moulopoulos LA, Granfield CAJ, Dimopoulos MA et al. Extraosseous multiple myeloma: imaging features. A J R 1993; 161: 1083–1087.

15. Mysliveček M, Bačovský J, Kamínek M et al. Technecium-99m-MIBI scintigraphy in multiple myeloma a sensitive index of biological activity of disease. Eur J Nuclear Medicine 2002; 29 (Suppl 1): 241.

16. Novák Z. Ultrasonografie štítné žlázy. In: Stárka L et al. Aktuální endokrinologie. Praha: Maxdorf 1999.

17. Ohshima M, Momiyama T, Souda S et al. Primary plasmacytoma of the thyroid: a case report and comparative literature study between Western nations and Japan. Pathol Int 1994; 44: 645–651.

18. Schiller VL, Deutsch AL, Turner RR. Multiple myeloma presenting as extramedullary plasmacytoma of the thyroid, advanced grade II–III plasmablastic type. Skeletal Radiol 1995; 24: 314–316.

19. Ščudla V, Bačovský J, Indrák K et al. Výsledky léčby a změna prognózy nemocných s mnohočetným myelomem v období předchozích 40 let v oblasti střední a severní Moravy – rozbor souboru 562 nemocných. Vnitř Lék 2002; 48: 707–717.

20. Ščudla V, Budíková M, Bačovský J et al. Vztah hladin solubilních cytoadhezivních molekul VCAM-1 a ICAM-1 k vybraným klinickým a laboratorním ukazatelům mnohočetného myelomu. Vnitř Lék 1999; 45: 583–590.

21. Ščudla V, Indrák K. Prognostic significance of stratification systems in multiple myeloma. I. Risk categories (good and poor risk). Neoplasma 1985; 32: 469–479.

22. Ščudla V, Indrák K. Prognostic significance of stratification systems in multiple myeloma. II. Clinical staging systems. Neoplasma 1985; 32: 481–493.

23. Vander JB, Gaston EA, Dawber TR. The significance of nontoxic thyroid nodules. Final report of a 15-year study of the incidence of thyroid malignancy. Ann Intern Med 1968; 69: 537–540.

24. Voegt H. Extramedulläre plasmocytome. Virchows Arch. Pathol Anat 1938; 302: 497–508.

25. Wanebo H, Geller W, Gerold F. Extramedullary plasmacytoma of the upper respiratory tract: recurrence after latency of thirty-six years. NY State J Med 1966; 66: 1110–1113.

26. Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine (Baltimore) 1976; 55: 217–238.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 1

2005 Issue 1

Most read in this issue
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#