Obesity and metabolic syndrome

Czech version

Authors: D. Zeman
Authors‘ workplace: II. interní klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta doc. MUDr. Miroslav Souček, CSc.
Published in: Vnitř Lék 2005; 51(1): 72-75
Category: Reviews

Overview

Obesity is associated with insulinresistance and metabolic syndrome. The correlation of the presence of abdominal or visceral obesity defined by waist circumference with the occurence of metabolic risk factors and metabolic syndrome is more significant than body mass index. Adipocytokine secretion activity of adipose tissue participates in the pathogenesis of metabolic syndrome. External factors can significantly modify the course of metabolic syndrome disease. Weight reduction is an effective therapeutical intervention. Complex therapeutical approach includes the cognitive behavioral intervention techniques, dietotherapy, regimen exercise measures, pharmacotherapy and surgical bariatric techniques.

Key words:
obesity – visceral obesity – adipose tissue – metabolic syndrome – therapy/treatment of obesity

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