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Vascular and psychosocial risk factor of Alzheimer's disease


Authors: J. Povová 1;  P. Ambroz 1;  H. Tomášková 1;  M. Bar 2;  O. Šerý 3;  J. Štěpánová 4;  K. Vařechová 1;  V. Janout 1
Authors‘ workplace: Lékařská fakulta Ostravské univerzity v Ostravě Ústav epidemiologie a ochrany veřejného zdraví Vedoucí: prof. MUDr. Vladimír Janout, CSc. 1;  Lékařská fakulta Ostravské univerzity v OstravěKatedra interních oborů LFVedoucí: MUDr. Ivo Valkovský 2;  Přírodovědecká fakulta Masarykovy univerzity v BrněÚstav biochemieŘeditel: doc. Ing. Martin Mandl, CSc. 3;  Krajská nemocnice Tomáše Bati, a. s., ZlínŘeditel: MUDr. Bohuslav Škubal, CSc. 4
Published in: Prakt. Lék. 2013; 93(2): 59-62
Category: Of different specialties

Overview

Alzheimer's disease (AD) is the most common form of dementia. It is a degenerative incurable terminal disease. AD affects a high percentage of persons all over the world. Aetiology is still unknown. Numerous etiological factors of AD have already been discovered. Pilot evaluation of 307 cases and 96 controls from mental hospitals in project “Epidemiology and genetic of Alzheimer´s disease” provided following results. The questionnaires contain questions about identification, education, lifestyle, vascular risk factors, hobbies, occupation, incidence of the disease in the family, results of Minimental State Examination (MMSE). Though there are the first results from pilot part of study, some questions are presented. Results suggest, that persons with AD have often a cardiovascular disease and head injury in history. Conversely they did not have diabetes mellitus, hypertension and cerebrovascular disease.

Keywords:
dementia – Alzheimer's disease – risk factors


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