Cardio-metabolic risks of obesity

Authors: MUDr. Fábryová Ľubomíra, PhD.
Authors‘ workplace: MetabolKLINIK s. r. o., Ambulancia pre diabetológiu, poruchy látkovej premeny a výživy, Špecializovaná lipidologická ambulancia, Bratislava
Published in: Forum Diab 2015; 4(1): 67-74
Category: Topic


Obesity is a progressive chronic disease characterized by accumulation of fat and association of many organ-specific metabolic and cardiovascular complications which affect the quality of life and its expectancy in obese subject. Cardio-metabolic complications of obesity are involved in denomination of metabolic syndrome characterized by insulin resistance, visceral obesity, systemic subclinical inflammation, disorders of coagulation and fibrinolysis, and currently, also by ectopic fat tissue. Different stages of impaired glucose tolerance, atherogenic dyslipidaemia, hypertension, disorders of coagulation and fibrinolysis are beyond metabolic syndrome in clinical practice. Obesity and previously mentioned clinical states impact the increase of cardiovascular disease (ischemic heart disease, myo­cardial infarction). Recent knowledge allows us to intervenient against the increase of cardiovascular diseases with prevention and complex management of obesity and cardiovascular risk factors

Key words:
atherogenic dyslipidaemia – cardio-metabolic diseases – diabetes mellitus – obesity


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