Diagnosis and treatment of Bartonella endocarditis


Authors: K. Kuncová 1;  H. Žemličková 1;  J. Jäger 2;  L. Ryšková 1;  L. Plíšková 3;  R. Bolehovská 3;  M. Pojar 4
Authors‘ workplace: Ústav klinické mikrobiologie Fakultní nemocnice Hradec Králové 1;  I. interní kardioangiologická klinika Fakultní nemocnice Hradec Králové 2;  Ústav klinické biochemie a diagnostiky Fakultní nemocnice Hradec Králové 3;  Kardiochirurgická klinika Fakultní nemocnice Hradec Králové 4
Published in: Epidemiol. Mikrobiol. Imunol. 68, 2019, č. 2, s. 104-108
Category: Short Communication

Overview

The Bartonella genus comprises more than 20 species of Gram-negative rods which are difficult to culture. These are facultative intracellular bacteria. Humans are reservoir hosts for B. quintana and B. bacilliformis or accidental hosts for other species. Bartonella is a cause of zoonosis. Bartonella infection can be completely asymptomatic or can be linked to various conditions. Our experience with Bartonella endocarditis from 2012–2017 is presented. The most effective diagnostic method for Bartonella endocarditis is PCR detection of DNA of the pathogen from excised valve tissue. The European Society of Cardiology (ESC) in the guidelines from 2015 recommends the combination doxycycline gentamycin for the treatment of Bartonella endocarditis.

Keywords:

Bartonella – endocarditis – diagnosis – treatment


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Hygiene and epidemiology Medical virology Clinical microbiology
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