Authors: J. Laco; A. Ryška; P. Čelakovský * Authors‘ workplace: Fingerlandův ústav patologie, LF UK a FN, Hradec Králové ; Klinika ušní, nosní a krční, LF UK a FN, Hradec Králové * Published in: Čes.-slov. Patol., 41, 2005, No. 1, p. 34-37 Category: Original Article
The case of an 83-year-old female with a history of a two months enlarging goiter is presented. Clinically, a firm goiter with fixation to surrounding soft tissues was found. Fine needle aspiration cytology was performed with the conclusion of a sarcomatoid variant of anaplastic carcinoma of the thyroid gland; biopsy was recommended. The patient was operated on and died six months after operation with metastatic dissemination in lymphatic nodes and lungs. Histologically, an invasive high-grade tumor composed of irregular, sometimes bizarre spindled or polygonal cells intermingled with foci of chondroid tissue was seen. The cartilage comprised lobularly arranged chondrocytes with irregular nuclei; bi - or multinucleated chondrocytes were present as well. The diagnosis of thyroid anaplastic carcinoma with chondrosarcomatous component was established. Differential diagnostics of this tumour is discussed.
Key words: thyroid gland – anaplastic carcinoma – chondrosarcoma
Don‘t have an account? Create new account
Enter the email address that you registered with. We will send you instructions on how to set a new password.
