Jan Janoušek: pioneer in resynchronization therapy for heart failure in children

Czech version

Authors: Jan Marek
Authors‘ workplace: University College London, Londýn, Velká Británie ; 1. lékařská fakulta, Univerzita Karlova, Praha ; Great Ormond Street Hospital for Children, Londýn, Velká Británie
Published in: Čes-slov Pediat 2026; 81 (3): 125-127.
Category: Short News
doi: https://doi.org/10.55095/CSPediatrie2026/024

Overview

Marek J. Jan Janoušek: pioneer in resynchronization therapy for heart failure in children

Cardiac resynchronization therapy (CRT) for heart failure is a well-established treatment method for children with dyssynchronous ventricular impairment. In combination with pharmacological therapy, it can significantly improve the clinical condition of patients, including those referred for heart transplantation. Jan Janoušek from the Children’s Cardiac Centre of University Hospital Motol, Prague, was among the first pediatric cardiologists worldwide to make a substantial contribution to the introduction of CRT for children with congenital or acquired cardiac disease. This report outlines the principles of CRT and presents the first results published by Jan Janoušek in American Journal of Cardiology in 2001.

Keywords:

Electrophysiology – cardiac resynchronization therapy – pediatric cardiology

Sources

1. Janoušek J, Vojtovič P, Hučín B, et al. Resynchronization pacing is a useful adjunct to the management of acute heart failure after surgery for congenital heart disease. Am J Cardiol 2001; 88(2): 145–152.

2. Janoušek J, Tomek V, Chaloupecký VA, et al. Cardiac resynchronization therapy: a novel adjunct to the treatment and prevention of systemic right ventricular failure. J Am Coll Cardiol 2004; 44(9): 1927–31.

3. Janoušek J, van Geldorp IE, Krupičková S, et al. Permanent cardiac pacing in children: choosing the optimal pacing site: a multicenter study. Circulation 2013; 127(5): 613–23.