Granulocyte Colony Stimulating Factor in the Treatment of Severe Neutropenia in Very LowBirth Weight Neonates
Authors:
Z. Straňák 1,2; S. Bělohlávková; J. Melichar; J. Janota; J. Kučera; J. Šimák 1
Authors‘ workplace:
Ústav pro péči o matku a dítě, Praha
1
Published in:
Čes-slov Pediat 2000; (4): 227-229.
Category:
Overview
The granulocyte-colony stimulating factor (G-CSF) was used in two extremely low birth weight infants withsevere neutropenia where sepsis was not confirmed. During 12 hours after the initial dose of 5 mg/kg/day of G-CSF(Granocyte 13, Rhone Poulenc) in combination with dexamethasone, a significant rise of the absolute neutrophilcount occurred and remained in the normal range. No side-effects were observed during the course of therapy.We suppose that G-CSF may be used in indicated cases of severe neutropenia in extremely premature newborns.
Key words:
extremely premature newborn, neutropenia, granulocyte-colony stimulati ng factor
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2000 Issue 4
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