Authors: Z. Straňák 1,2; S. Bělohlávková; J. Melichar; J. Janota; J. Kučera; J. Šimák 1 Authors‘ workplace: Ústav pro péči o matku a dítě, Praha 1 Published in: Čes-slov Pediat 2000; (4): 227-229. Category:
The granulocyte-colony stimulating factor (G-CSF) was used in two extremely low birth weight infants withsevere neutropenia where sepsis was not confirmed. During 12 hours after the initial dose of 5 mg/kg/day of G-CSF(Granocyte 13, Rhone Poulenc) in combination with dexamethasone, a significant rise of the absolute neutrophilcount occurred and remained in the normal range. No side-effects were observed during the course of therapy.We suppose that G-CSF may be used in indicated cases of severe neutropenia in extremely premature newborns.
Key words: extremely premature newborn, neutropenia, granulocyte-colony stimulati ng factor
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