Lupus Miliaris Disseminatus Faciei. Case report
Authors:
M. Důra 1,2; L. Lacina 1,3,4; O. Kodet 1,3,4; J. Horažďovský 5; J. Štork 1
Authors‘ workplace:
Dermatovenerologická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. Jiří Štork, CSc.
1; Ústav patologie 1. LF UK a VFN, Praha, přednosta prof. MUDr. Pavel Dundr, Ph. D.
2; Anatomický ústav 1. LF UK, přednosta prof. MUDr. Karel Smetana, DrSc.
3; BIOCEV, vedoucí laboratoře prof. MUDr. Karel Smetana, DrSc.
4; Kožní oddělení, Nemocnice České Budějovice, a. s., primář MUDr. Jiří Horažďovský, Ph. D.
5
Published in:
Čes-slov Derm, 93, 2018, No. 5, p. 181-184
Category:
Case Reports
Overview
The authors describe a case of a 34-year-old man, who developed caseous granulomas on his face and nape that kept relapsing for 11 years and were diagnosed as lupus vulgaris at first. Anti-tuberculosis treatment that lasted one year led to healing of the lesions with scars left behind. After 4 years the lesions relapsed with the same histologic picture and were diagnosed as lupus miliaris disseminatus faciei. Pulmonary examination, TB culture test, PCR test of tissue sample for mycobacterium species and QuantiFERON TB Gold test were all negative, Mantoux test was 20 mm in diameter. Minocycline in dose of 200 mg a day led to nearly complete healing of the lesions, however the treatment was stopped after 18 months because of stationary clinical picture. During the last check-up, 3 years after the end of the treatment, a few new papules on the nape, face and arm are were noted. According to phone conversation, a solitary, spontaneously subsiding lesion kept coming back every six months for 2 years, but there was no recurrence of lesions for the last four years. So, the disease resolved after 18 years of duration.
Key words:
lupus vulgaris – lupus miliaris disseminatus faciei – extrafacial manifestation – antituberculosis drugs – minocycline – spontaneous remission after 18 years
Sources
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Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2018 Issue 5
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