Skin Aspergillosis in a Patient after Allogenic Transplantation of HaematopoieticStem Cells

Authors: P. Cetkovská 1;  K. Pizinger 1;  M. Karas 2
Authors‘ workplace: Dermatovenerologická klinika, LF UK Plzeň přednosta prof. MUDr. Vladimír Resl, CSc. 2Hematologicko-onkologické oddělení, FN Plzeň vedoucí prim. MUDr. Vladimír Koza 1
Published in: Čes-slov Derm, , 2002, No. 5, p. 213-216


Skin infections are a frequent complication associated with transplantation of haematopoieticstem cells, as due to reduced immunity the patients develop otherwise quite rare opportuneinfections. The manifestations may be localized only in the skin or affect also other organs. As anexample of disseminated infection the authors present the case of a 48-year-old man treated byallogenic transplantation of peripheral stem cells who developed seven months after transplantationdisseminated skin aspergillosis. Concurrently signs of cytomegaloviral and bacterial infection weredetected and despite intense anti-infectious therapy the patient died. In immunosuppressed patientsit is important to keep in mind the increasing incidence of various skin infections which may takean atypical course and have a very adverse prognosis.

Key words:
skin aspergillosis - disseminated form - allogenic transplantation of haematopoieticstem cells - infectious diseases in immunosuppressed patients

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Dermatology & STDs Paediatric dermatology & STDs
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