Relapsing Erysipelas - Initial Experience with Oral Vaccination Treatment

Authors: M. Viktorinová 1;  I. Karlová 1;  D. Koukalová 2;  Y. Lovečková 2
Authors‘ workplace: Klinika chorob kožních a pohlavních LF UP a FN, Olomouc, přednosta doc. MUDr. M. Buček, CSc. 2Ústav mikrobiologie LF UP, Olomouc, přednostka doc. MUDr. D. Koukalová, CSc. 1
Published in: Čes-slov Derm, , 2002, No. 4, p. 163-167


In a group of 17 patients with relapsing erysipelas bacterial vaccine in the form of dropscontaining strains of Klebsiella pneumoniae, Staphylococcus aureus and Propionibacterium acnes ata ratio of 1:1:1 was used for treatment.The patient took 10 drops in the morning on fasting according to a schedule written in thecalendar. The first course comprised 22 doses, the second one 10 doses after three weeks and thethird course after six weeks 5 doses. Maintenance doses (always for a 5-day period) were used at firstat two, later up to six-month intervals depending on the clinical condition. Concurrently externaldrugs were used to treat possible sites of penetration of the infection, i.e. leg ulcers, mycoticinfections of the feet and other dermatoses.During the follow up period of 1-6.3 years 12 (70.6 %) patients were free from a relapse oferysipelas, in another five (29.4 %) during the relapse the course was much milder, the temperatureswere lower and healing after antibiotic treatment more rapid.It was found that oral vaccination treatment of patients with relapsing erysipelas can havea favourable impact on the subsequent course of the disease.

Key words:
relapsing erysipelas - treatment - oral vaccines

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Dermatology & STDs Paediatric dermatology & STDs
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