Granulomatosis Orofacialis in Two Monozygotic Twins

Czech version

Authors: K. Kolibášová ¹; E. Hegyi ¹; Z. Lukáčová ¹; M. Buc ²; M. Lukáčová ³; A. Doležalová ⁴; M. Hrubiško ⁵; F. Ondriaš ⁶
Authors‘ workplace: Kožná klinika Slovenskej Postgraduálnej Akadémie Medicíny (SPAM), NsP Ružinov, Bratislava prednostka doc. MUDr. Klaudia Kolibášová, PhD. 2Imunologický ústav Lekárskej fakulty Univerzity Komenského, Bratislava prednosta prof. MUDr. Milan Buc, DrSc. 3Centru ¹
Published in: Čes-slov Derm, , 2002, No. 4, p. 172-174
Category:

Overview

The authors detected monozygotic twins who developed at the age of 30 years permanent notpainful oedema of the lower lip. In the case-history oedema of the lip was recorded in the probands’grandmother. Epicutaneous tests (the patients grow vegetables and flowers) were negative. As toroutine tests the early response to Peru balsam was positive, in one sibling also the late response topropolis. Histological examination confirmed the diagnosis of granulomatous cheilitis. Wedge-shapedexcision from the lower lip and administration of metronidazol were not successful.

Key words:
granulomatosis orofacialis - monozygotic twins - familiar occurrence

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Article was published in

Czech-Slovak Dermatology

2002 Issue 4