Diffuse idiopathic skeletal hyperostosis (DISH) in old age, exceptionally deforming disease

Authors: A. Pavelková
Authors‘ workplace: Revmatologický ústav Praha
Published in: Čes. Revmatol., 16, 2008, No. 3, p. 119-123.
Category: Case Report


Diffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory skeletal disease characterized by hyperostosis in the area of both axial skeleton and periphery. It develops after the 40th year of age and manifests most frequently in the middle and higher age. Its association with type 2 diabetes mellitus and other metabolic disorders, hyperuricemia and metabolic disorder of lipids, has been known for some years already, although the relationship is not completely clear yet. This disease is often linked with common vertebrogenic ailment, which corresponds with its intensity to degenerative spine disease, however, it can also lead to a severe deforming involvement with great clinical distress. The manifestations of the disease are clinically and objectively close to ankylosing spondylitis.

Key words:
DISH, hyperostosis, diabetes mellitus, insulin resistence


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Dermatology & STDs Paediatric rheumatology Rheumatology
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