Nine-valent HPV vaccine - new generation of HPV vaccine

Authors: T. Fait 1,2;  V. Dvořák 1,4;  R. Pilka 1,3
Authors‘ workplace: HPV College o. s., prezident MUDr. J. Ondruš, CSc., MIAC 1;  Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc. 2;  Porodnicko-gynekologická klinika FN a LP UP, Olomouc, přednosta prof. MUDr. R. Pilka, Ph. D. 3;  Centrum ambulantní gynekologie a primární péče, Brno 4
Published in: Ceska Gynekol 2015; 80(6): 397-400


To evaluate current knowledge about new generation of HPV vaccine – nine-valent vaccine Gardasil9.

Review article.

The nine-valent vaccine against HPV 6/11/16/18/31/33/45/52/58 could improve efficacy of quadrivalent vaccine from 70 to 90 percent for cervical cancer. In addition this vaccine has covered around85-90% of HPV-related vulvar, vaginal and anal cancers. Efficacy and immunogenicity against HPV 6/11/16/18 is the same as for quadrivalent vaccine. Efficacy against HPV 31/33/45/52/58 associated lesions is 97%.

HPV infection, prevention, nine-valent HPV vaccine


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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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