I. Mikyšková 1; M. Michal 2
Bioptická s. r. o., vedoucí lékařka prof. MUDr. A. Skálová, CSc. 2Šiklův patologicko-anatomický ústav FN, Plzeň, přednosta prof. MUDr. M. Michal
Čes. Gynek.2004, , č. 6 s. 510-516
Objective: Human papillomaviruses (HPV) are linked to broad spectrum of epithelial lesions, wellknown is their main role in ethiology of cervical carcinoma. HPV testing is an integral componentof cervical cancer screening.This article presents general overview of molecular biologic methods current used in HPV diagnostic.Methods are divided according to its principle to three groups – hybridization based, PCRbased and combined both of this principle. The review would help select optimum methodics forroutinely screening, for causal clinical diagnostics of HPV associated diseases or for research study.From this context arise need of theoretical rudiments and experience for HPV diagnostics.Subject: Review article.Setting: Sikl’s Department of Pathology, Charles University, Medical Faculty Hospital Pilzen,Czech Republic.
Key words: human papillomaviruses, HPV, HPV testing
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Gynaecology and obstetrics