PretermRupture of Membranes after Amniocentesis in the 2nd Trimesterand Evaluation of Fibrin Sealing: Case Report

Authors: Ľ. Janek;  M. Križko;  V. Ferianec;  K. Holomáň;  B. Čižmár
Authors‘ workplace: II. gynekologicko-pôrodnická klinika LFUK, NsP Ružinov, Bratislava, prednosta prof. MUDr. K. Holomáň, CSc. Department of Obstetrics and Gynecology, Spectrum Health – Blodgett Campus, Grand Rapids, USA, prednosta: Newton Ch. W., MD
Published in: Čes. Gynek.2002, , č. 2 s. 71-74


The aim of this study was to evaluate fibrin sealing in management of prematurerupture of membranes after amniocentesis in early second trimester.Design: Case report.Setting: II. gynekologicko-pôrodnícka klinika LFUK NsP Ružinov, Bratislava; Department of Ob-stetrics and Gynecology, Spectrum Health – Blodgett Campus, Grand Rapids, USA.Subject and Method: In this case report authors report the use of fibrin sealant (Tissucol KIT,Immuno, A) in management of premature rupture of membranes after genetic amniocentesis. The sealing was performed in 19 + 0 week of pregnancy, 15 days after amniocentesis. The pregnancywas terminated by caesarean section in 34-th week, 98 days after sealing. The newborn was instable condition, without clinical or laboratory signs of infection. No sceletal deformities or ad-verse efects of fibrin sealant were observed. Neurological examination in 3 month of age evalua-tes the psychomotorical development as normal.Conclusion: We consider the perinatal outcome of this pregnancy as positive.

Key words:
fibrin sealant, preterm rupture of maembranes, amnicentesis, Tissucol

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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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