Age-related macular degeneration

Authors: I. Fišer
Published in: Čes Ger Rev 2010; 8(1-2): 33-39


Age-related macular degeneration (AMD) is the most common cause of vision loss in developed countries in people older than 55 years. The wet form of this disease is the cause of severe vision impairment in 90 percent of patients. AMD develops as a result of an interaction between genetic and lifestyle factors. The key mechanism in the development of wet AMD is the growth of new vessels, stimulated by the vascular endothelial growth factor (VEGF). The treatment of choice is, therefore, the use of anti-VEGF agents administered as intravitreal injections. International clinical studies are evaluating new AMD treatments. It is necessary to start the treatment early, before severe visual impairment occurs.

Key words:
age-related macular degeneration – anti-VEGF – Avastin


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Geriatrics General practitioner for adults
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