Acute disseminated encephalomyelitis (ADEM) – Case Report
Authors:
Dostálová Vlasta; Dostál Pavel; Černý Vladimír
Authors‘ workplace:
Klinika anesteziologie, resuscitace a intenzivní medicíny, Fakultní nemocnice Hradec Králové
Published in:
Anest. intenziv. Med., 19, 2008, č. 4, s. 203-209
Category:
Intesive Care Medicine - Case Report
Overview
Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinisation of the brain and spinal cord, precipitated by a infection or vaccination. In the past ADEM was a rare disease with higher incidence recently. Although history, clinical and radiological presentations are typical for this disease, the diagnosis is made per exclusionem. ADEM requiring ICU admission is a severe disease causing high mortality and persistent disability. Authors describe course of illness in one patient, diagnostic process a and therapy with corticosteroids, IVIG a plasmapheresis.
Key words:
acute disseminated encephalomyelitis – intensive care – corticoterapy – IVIG – plasmapheresis
Sources
1. Tenembaum, S. et al. International Pediatric MS Study Group. Acute disseminated encephalomyelitis. Neurology, 2007, 68, 16, p. 23–36.
2. Dale, R. C. et al. Early relapse risk after a first CNS inflammatory demyelination episode: examining international consensus definitions. Dev. Med. Child Neurol., 2007, 49, 12, p. 887–893.
3. Cohen, O. et al. Recurrence of acute disseminated encephalomyelitis at the previously affected brain site. Arch. Neurol., 2001, 58, 5, p. 797–801.
4. Bennetto, L. et al. Encephalomyelitis inflammatory/post-infectious. J. Neurol. Neurosurg. Psychiatry, 2004, 75, p. 22–28. Dostupné na: http://jnnp.bmj.com/cgi/content/full/ 75/suppl_ 1/i22.
5. Menge, T. et al. Acute disseminated encephalomyelitis: an acute hit against the brain. Curr. Opin. Neurol., 2007, 20, 3, p. 247–254.
6. Robert, R. et al. Acute Disseminated Encephalomyelitis. Article Last Updated, 2007, 12 doi:10.1136/jnnp.2004.045500
7. Menge, T. et al. Acute Disseminated Encephalomyelitis. An Update. Arch. Neurol., 2005, 62, p. 1673–1680.
8. Plesner, A. M. et al. Neurological complications to vaccination against Japanese encephalitis. Eur. J. Neurol., 1998, 5, p. 479–485.
9. Chopra, B. et al. CSF Beta-1 Globulin – A Potential Marker in Differentiating Multiple Sclerosis and Acute Disseminated Encephalomyelitis: A Preliminary Study. Code Number: ni02011. Dostupné na: http://www.neurologyindia.com
10. Schwarz, S. et al. Acute disseminated encephalomyelitis: a follow-up study of 40 adult patients. Neurology, 2001, 56, p.1313–1318.
11. Maramattom, B. V. et al. Clinical features and outcome of acute disseminated encephalomyelitis (ADEM): An outlook from South India. Ann. Indian. Acad. Neurol., 2006, 9, p. 20–24. Dostupné na: http://www.annalsofian.org/text.asp? 2006/9/1/20/22817
12. Rossi, A. Imaging of acute disseminated encephalomyelitis. Neuroimaging Clin. N. Am., 2008, 18, 1, p. 149–161.
13. Sekula, R. F. et al. Central brain herniation secondary to fulminant acute disseminated encephalomyelitis: implications for neurosurgical management. Case report. J. Neurosurg., 2006, 105, 3, p. 472–474.
14. Ravaglia, S. et al. Severe steroid-resistant post-infectious encephalomyelitis: general features and effects of IVIg. J. Neurol., 2007, 254, 11, p. 1518–1523.
15. Lu, R. P. et al. Combination regimen of methylprednisolone, IV immunoglobulin, and plasmapheresis early in the treatment of acute disseminated encephalomyelitis. J. Clin. Apher., 2006, 21, 4, p. 260–265.
16. Lin, CH. et al. Acute disseminated encephalomyelitis: a follow-up study in Taiwan. J. Neurol. Neurosurg. Psychiatry, 2007, 78, 2, p. 162–167.
17. Sonneville, R. et al. Acute disseminated encephalomyelitis in the intensive care unit: clinical features and outcome of 20 adults. Intensive Care Med., 2008, 34, 3, p. 528–532.
18. Tenembaum, S. et al. Acute disseminated encephalomyelitis: a long-term follow-up study of 84 pediatric patients. Neurology, 2002, 59, p. 1224–31.
19. Axer, H. et al. Initial DWI and ADC imaging may predict outcome in acute disseminated encephalomyelitis: report of two cases of brain stem encephalitis. J. Neurol. Neurosurg. Psychiatry, 2005, 76, p. 996–998. Dostupné na: http://jnnp.bmj.com/cgi/content/full/76/7/996.
20. Rutchik, J. S. et al. Neurologic issues with solvents. Clin. Occup. Environ. Med., 2004, 4, 4, p. 621–656.
21. Matsuoka, M. Neurotoxicity of organic solvents—recent findings. Brain Nerve, 2007, 59, 6, p. 591–596.
22. Thuomas, K. A. et al. MR imaging in solvent-induced chronic toxic encephalopathy. Acta Radiol., 1996, 37, 2, p. 177–179.
Labels
Anaesthesiology, Resuscitation and Inten Intensive Care MedicineArticle was published in
Anaesthesiology and Intensive Care Medicine
2008 Issue 4
Most read in this issue
- Acute disseminated encephalomyelitis (ADEM) – Case Report
- Antimicrobial protection options in central venous catheters – Overview
- Acute theophylline intoxication – Case report
- Treatment of acute heart failure syndrome – review