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Impact of Primary Tumor Location and Early Regression on Survival in Patients with Metastatic CRC

15. 9. 2020 Source: Colorectal Cancer

Results from recent clinical studies suggest the prognostic significance of the primary tumor location on the survival of patients with metastatic colorectal cancer (mCRC). A retrospective analysis of data from a single-arm open-label phase II clinical trial evaluated the impact of primary tumor location and its early regression (ETS -⁠ early tumor shrinkage) on the survival of patients with mCRC who received a combination of chemotherapy (FOLFIRI regimen) and targeted biological therapy (panitumumab).

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Mass in the Left Atrium Appendage -⁠ Case Report

A symptomatic mass in the left atrial appendage warrants thorough investigation and radical treatment –⁠ unless it is in the heart of a polymorbid patient, as was the case in the following report.
14. 9. 2020 Source: Thromboprophylaxis
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Patient with Generalized Melanoma Treated with Nivolumab with Long-Term Response after Previous Failure of Combined Chemoimmunotherapy

11. 9. 2020 Source: Case Studies from Immunooncology
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Patient Treated with Nivolumab After Previous Failure of BRAF Inhibitor Therapy

11. 9. 2020 Source: Case Studies from Immunooncology
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Side Effects of Metformin: It's Not Just a Nocebo Effect?

If we were to name medications that have the greatest significance from a population standpoint, metformin would certainly be at the top of the list. We have known it for over fifty years and know a…
11. 9. 2020 Source: Modern Treatment of Diabetes
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Patient with generalized malignant melanoma treated with nivolumab in the first line

A 75-year-old patient was referred for examination at the dermato-oncology clinic of the Dermatology Clinic of VFN in September 2016. He was being treated for ICHS and had undergone prostate surgery for...
10. 9. 2020 Source: Case Studies from Immunooncology
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Odor in Incontinence is a Common Concern of Patients

Urinary incontinence represents a significant stigma, which usually deprives the affected person of all social contact, work and leisure activities, as well as intimate life. According to statistics,…
9. 9. 2020 Source: Incontinence
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Urinary Incontinence in Old Age as the Most Frequent Medical Problem

In patients over 65 years of age, incontinence occurs more frequently than cancer or cardiovascular diseases. Urine leakage significantly reduces the quality of life for seniors, worsens their…
9. 9. 2020 Source: Incontinence
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Effect of Zolpidem on Sleep Quality and Other Parameters in Patients During the Perioperative Period

Sleep quality is an important factor influencing functional outcomes, pain intensity, and patient satisfaction during the perioperative period. Sleep disturbances are a common problem among patients…
9. 9. 2020 Source: Geriatric Patient

Postoperative Wound Healing

Postoperative wound healing requires sufficient attention to prevent the development of complications that could impair the final functional and aesthetic outcome. This article aims to highlight important...
3. 9. 2020 Source: Wound Healing
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Sport and Programmed Sports Therapy in Hemophiliacs

Sport and physical activity are increasingly becoming an integrated part of the treatment plan for hemophiliacs. It was not long ago that sports were almost forbidden for these patients. The…
2. 9. 2020 Source: Hemophilia with Movement
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Physical Activity in Hemophiliacs and How to Ensure it Safely

Physical activity is beneficial −⁠ and this holds true for patients with hemophilia as well. New therapeutic modalities offer additional possibilities to optimize prevention so that, among other…
2. 9. 2020 Source: Hemophilia with Movement
pacient lékař konzultace prohlídka

Focus on the Connections Between Gastroesophageal Reflux Disease and COPD Exacerbations

In recent years, evidence has emerged of a higher prevalence of gastroesophageal reflux disease (GERD) in patients with chronic obstructive pulmonary disease (COPD). GERD symptoms are more common in…
1. 9. 2020 Source: Treatment of Asthma and COPD
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Digital Technology in COPD Therapy: Current Options and Future Prospects

This year, digital technologies have demonstrated their advantages in interpersonal communication, administrative processes, and in the field of medicine. The global crisis triggered by the…
1. 9. 2020 Source: Treatment of Asthma and COPD
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Comparison of the Efficacy and Safety of Two Enoxaparin Dosing Regimens in Patients After Chest Surgery

Effective prevention of thromboembolic disease in patients undergoing chest surgery is one of the key therapeutic goals. However, the question remains as to what dose of low molecular weight heparin…
31. 8. 2020 Source: Thromboprophylaxis
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