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Excellent effect of sotorasib in a higher line of treatment in a patient with NSCLC with G12C mutation of KRAS – a case study
We present a case study of an elderly patient with non-small cell lung cancer (NSCLC) treated with the selective KRASG12C inhibitor sotorasib in the 5th line of oncological treatment, but with a very exceptional effect.

Fluoroscopically Calibrated 3D-Printed Tools Increase Osteotomy Precision During Tumor Resection Near Joints
The area around the knee is a common site for malignant bone tumors, such as osteosarcomas. Their…

Intermittent Fasting May Carry Significant Health Risks
Results from an observational study presented at this year’s American Heart Association (AHA)…

Smaller Volume and Faster Infusion Rate of aPCC: What Do Current Data Say About This Modification?
Administering an infusion of activated prothrombin complex concentrate (aPCC) at the standardized rate...

Portal Vein Thrombosis as a Complication of COVID-19 Infection – A Case Study
COVID-19 Infection is Associated with a Higher Risk of Thrombotic Complications. Many cases of deep...

Experience with 20% subcutaneous immunoglobulin in the treatment of primary immunodeficiency
Patients with primary antibody deficiency are administered immunoglobulin (Ig) replacement therapy to...

The Benefit of Liposomal Irinotecan in the Treatment of Pancreatic Cancer in a Young Patient – A Case Study
Pancreatic tumors continue to be a challenge in modern oncology. Due to the asymptomatic nature of…

Each Missed Dose of Thromboprophylaxis in Trauma Patients Significantly Increases the Risk of VTE
Available data shows that enoxaparin prophylaxis effectively reduces the incidence of venous thromboembolism...

Biosimilars in the Prophylaxis of Venous Thromboembolism
Hospitalized patients with internal diseases or after surgery have an increased risk of venous thromboembolism...

Technology allows children in palliative care to escape from the hospital room for a while
Children's palliative care is a field that is just developing in our country. Palliative teams are…
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