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COPD is Treated Differently Across Europe –⁠ What Could Be the Reasons for This Variability?

24. 5. 2022 Source: Cough Therapy

As part of this year's Hradec Pneumological Days (HPD 2022), the head of the Pulmonary Clinic at Charles University Faculty of Medicine and University Hospital Hradec Králové, Assoc. Prof. Vladimír Koblížek, M.D., Ph.D., reflected on the different rates of prescription of mucoactive drugs to COPD patients in various European countries. According to him, it is clear that in real practice, this treatment works. So what is the reason for its varying prescription across the old continent?

bolest břicha starší muž senior

Prolonged Course of Metastatic Stomach Cancer with Long-term Stabilization –⁠ Case Report

In the following case report, we present the case of a patient with a prolonged oncological disease –⁠ stomach cancer. The patient has been asymptomatic for a long time and in good performance status…
24. 5. 2022 Source: Treatment of Gastrointestinal Carcinomas
statistika grafy výzkum

Focused on MS: Statistics Are Boring, But They Have Valuable Data!

What is the prevalence of multiple sclerosis? Has the proportion of patients treated with highly effective therapy changed? We bring you the latest data from around the world and domestically.
23. 5. 2022 Source: Multiple Sclerosis
mozek mri scan roztroušená skleróza

Epstein-Barr Virus –⁠ Is the Culprit of MS Revealed?

Could the Epstein-Barr virus hold the answer to the etiology of multiple sclerosis? A dataset of over 10 million American recruits offered intriguing insights. You may have encountered the…
23. 5. 2022 Source: Multiple Sclerosis
testování biomarkerů

From Biomarker Testing to NSCLC Treatment Selection

During a satellite symposium at this year's European Lung Cancer Congress (ELCC 2022), Prof. Martin Reck from the Department of Thoracic Oncology at the hospital in Grosshansdorf, Germany, discussed…
23. 5. 2022 Source: Non-Small Cell Lung Cancer
porod_miminko

Is Adding Fibrinogen Concentrate to Transfusion Therapy for Postpartum Hemorrhage an Effective Approach?

Significant postpartum hemorrhage can be managed with fresh frozen plasma transfusion. However, administering larger volumes is associated with several risks. The authors of the Japanese study below…
20. 5. 2022 Source: Life-threatening Bleeding
operace_krev

Administration of Fibrinogen Concentrate in Patients with Persistent Bleeding After Cardiac Surgery

Is the administration of fibrinogen concentrate in patients with persistent bleeding after initial cardiac surgery associated with an increased risk of thromboembolic events or death? Authors of a…
20. 5. 2022 Source: Life-threatening Bleeding
Kolorektální karcinom_obr_kazuistika

Treatment of a patient with colorectal cancer after kidney transplantation –⁠ case report

Patients after organ transplantation currently live to an older age thanks to advances in surgery and pharmacotherapy. However, the longer a person takes immunosuppressants, the more they are at risk…
20. 5. 2022 Source: Colorectal Cancer
diabtes lipidy jídlo

Prediction of DM2 and CVD Development Risk Based on Lipidomic Risk Determination

The incidence of type 2 diabetes mellitus (DM2) and cardiovascular diseases (CVD) is strongly influenced by lifestyle and diet. Hypertension, hypercholesterolemia, and elevated blood glucose are…
20. 5. 2022 Source: Modern Treatment of Diabetes
Psychiatr_mladá žena

Psychiatry of Transitional Age −⁠ An Important Area That Has Not Yet Received Much Attention

Three-quarters of psychiatric disorders develop before the age of 25, with up to half of these disorders appearing before the age of 16. The period of so-called emerging adulthood thus represents a…
19. 5. 2022 Source: Modern Treatment of Schizophrenia
rakovina buňky

Erlotinib in Conditions of Routine Clinical Practice

The patient population in clinical trials is always somewhat selected. Only a well-conducted analysis of real-world clinical practice data can provide a clearer picture of the efficacy and safety of…
18. 5. 2022 Source: Oncological Treatment
otazníky

What can we base the decision on for the choice of initial treatment modality for CLL?

We now have a range of highly effective treatment options for patients with chronic lymphocytic leukemia (CLL). New drugs have significantly contributed to improved overall survival (OS). However,…
18. 5. 2022 Source: Chronic Lymphocytic Leukemia
Guidelines_kompas

Update of International Recommendations for the Diagnosis and Treatment of Hereditary Angioedema from 2021

The aim of the 2021 update of the recommendations for the diagnosis and treatment of hereditary angioedema (HAE) is to help doctors answer important clinical questions: How to diagnose HAE? When and…
18. 5. 2022 Source: Hereditary Angioedema
klouby, kolena, šlachy, vazy

Management of Musculoskeletal Issues in Hemophiliacs at a Glance

Musculoskeletal issues are among the most common complications of hemophilia. Prevention and early treatment are crucial, and this message is also addressed to specialists by the World Federation of…
17. 5. 2022 Source: Hemophilia with Movement
onkology

Progress on Lorlatinib –⁠ What's Next?

Lorlatinib is currently mainly used in the 2nd and later lines of treatment for non-small cell lung cancer (NSCLC) with ALK gene rearrangement. Clinical research is now focusing on the question of…
17. 5. 2022 Source: Genetic Profile and Treatment of NSCLC
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