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velkobuněčný difuzní lymfom

Brentuximab vedotin in combination with lenalidomide and rituximab in R/R DLBCL –⁠ results from the open part of the ECHELON-3 study

10. 8. 2022 Source: Hematologic Malignancies

The aim of the open run-in phase of the randomized placebo-controlled phase III ECHELON-3 study, the results of which were presented at the ASCO and EHA 2022 congresses, was to evaluate the efficacy and safety of the brentuximab vedotin/lenalidomide/rituximab (BV-len-R) triplet in patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL).

pacient s klasickým Hodgkinovým lymfomem

6-year data from the ECHELON-1 study: How does combining brentuximab vedotin with chemotherapy affect overall survival of previously untreated cHL patients?

At this year's annual congress of the European Hematology Association (EHA), results from the analysis of 6-year data from the international randomized open-label phase III ECHELON-1 study on overall…
10. 8. 2022 Source: Hematologic Malignancies
amputovana noha

How to Save a Leg from Amputation?

Feared complications in diabetics include defects in typical locations on the lower limbs. Their presence and frequent recurrences increase the risk of possible amputation of varying degrees, mainly…
10. 8. 2022 Source: Wound Healing
lékař radost malý kluk a matka

Prophylaxis EHL products FVIII bring improvements in clinical and pharmacokinetic results

A freshly published real-world clinical practice study from Spain highlights the experience of switching patients with hemophilia A in a prophylaxis setting from standard half-life products to newer…
8. 8. 2022 Source: Hemophilia
Emotional joyful patient telling his doctor good news

Benefit of Adding Empagliflozin to Standard Therapy in Heart Failure with Reduced Ejection Fraction

The use of empagliflozin led to a reduction in the risk of hospitalization for heart failure or death from cardiovascular (CV) causes in the EMPEROR-Reduced study in patients with adequately treated…
5. 8. 2022 Source: Heart Failure
venclyxto kazuistika

Sequential administration of immunochemotherapy and venetoclax after failure of BCR inhibitor treatment –⁠ interactive video case study

The treatment of chronic lymphocytic leukemia (CLL) is evolving. What was impossible years ago is now becoming a reality. From chemotherapy, through immunochemotherapy, to the use of molecules…
5. 8. 2022 Source: Chronic Lymphocytic Leukemia
HydroClean

Hydroresponsive Dressings for Acute and Hard-to-Heal Wounds

A recently published review of clinical evidence from nearly three dozen studies demonstrates successful debridement and cleansing of various hard-to-heal wounds using HydroClean hydroresponsive…
4. 8. 2022 Source: Wound Healing
diabetes hladiny graf

Prediabetes through the lens of current data and findings −⁠ and why hurry with intervention

Type 2 diabetes mellitus (DM2) is one of the most common causes of premature morbidity and mortality worldwide. The most serious impact on the health of the organism is mainly due to the…
27. 7. 2022 Source: Diabetes
rheumatoid arthritis ilustrace

Discontinuation of Methotrexate After Initiation of Tofacitinib in the Treatment of Rheumatoid Arthritis

New real-world data show that in patients with rheumatoid arthritis (RA) who started treatment with tofacitinib combined with oral methotrexate (MTX), it is possible to discontinue MTX and achieve…
27. 7. 2022 Source: Arthritis
žilní tromboembolie

Incidence of CV Events, Malignancies, and Venous Thromboembolism in Patients with RA According to Baseline CV Risk and Administered Treatment

An international team of experts evaluated the impact of cardiovascular (CV) risk on the incidence and risk of major CV events, malignancies, and venous thromboembolism (VTE) in patients with…
27. 7. 2022 Source: Arthritis
The person suffers from hypoglycemia.

Increase in Hematocrit During Empagliflozin Treatment in a Diabetic Patient with Severe Anemia −⁠ A Case Study

In a case study involving a 78-year-old diabetic patient, where only the administration of empagliflozin led to the correction of severe anemia of unknown origin, Polish authors demonstrate the…
26. 7. 2022 Source: Heart Failure
IBS NEW

Composition of the Intestinal Microbiota of Patients with IBS May Predetermine the Success of a Diet with Low Fermentable Carbohydrates

Some patients with irritable bowel syndrome may benefit from a diet low in fermentable carbohydrates, but the mechanism of this intervention is not yet satisfactorily explained. A study published in …
23. 7. 2022 Source: Irritable Bowel Syndrome
covid srdce

Can the use of sartans reduce mortality and severity of COVID-19 in hypertensives?

Existing scientific and clinical evidence suggests the involvement of the renin-angiotensin-aldosterone system (RAAS) in the pathophysiology of COVID-19. Some of the initial experimental therapy…
21. 7. 2022 Source: Sartans in the Treatment of Hypertension
Diagnostika kožních malignit

Diagnosis of Skin Malignancies via Mobile Application Successfully Tested in the UK

Skin malignancies are a significant global cause of morbidity and mortality, with melanoma responsible for most deaths, and its incidence is increasing faster than any other cancer. Early detection…
21. 7. 2022 Source: proLékaře.cz
konzultace s mladými muži o rakovině prostaty

Early Detection of Erectile Dysfunction in Men with Type 2 Diabetes

A retrospective study published last year identified predictors of erectile dysfunction in men with type 2 diabetes. The authors recommend screening patients with elevated uric acid levels, diabetes…
18. 7. 2022 Source: Diabetes
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