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Alopecia Areata – Autoimmune Inflammatory Disease and a New Targeted Treatment Option
31. 10. 2022 Source: Biological TreatmentAlopecia areata (AA) is one of the non-scarring focal alopecias. It is an autoimmune disease of the hair follicle, the etiopathogenesis of which is not entirely understood. At the hair root, a lymphocytic inflammatory infiltrate develops, resulting in follicle miniaturization and the growth of a thin dystrophic hair. Recently, however, a new strategy for the treatment of AA has emerged, focusing on reducing inflammation of the hair follicle by inhibiting Janus kinases (JAK). This is the first therapeutic modality officially approved for this…
Contact Dermatitis in Patients with Venous Ulcers – and How to Prevent It?
The prevalence of chronic wounds increases with the rising average age, and for example, venous ulcers affect up to 2% of the global population. Materials used for wound coverage, however, present a…31. 10. 2022 Source: Wound Healing
Prim. Václava Adámková: People mistakenly believe that there are enough antibiotics and that they will always handle infections
According to the World Health Organization (WHO), by 2050, infections untreatable with antibiotics could become the leading cause of death, surpassing cardiovascular and oncological diseases. Rising…26. 10. 2022 Source: Anti-Infectives
Options for Tapering TPO-RA in ITP Patients: Practical Experience and Expert Consensus
A recently published British study aims to provide recommendations on tapering TPO-RA in patients with immune thrombocytopenia (ITP) based on existing evidence, survey results of clinical practice…25. 10. 2022 Source: Immune Thrombocytopenia
Effect of Romiplostim in Refractory ITP with Possibility of Maintaining Response Without Treatment – Case Report
This case report from the United States features an ideal therapeutic response to romiplostim in a patient with refractory immune thrombocytopenia (ITP). After several years of successful therapy,…25. 10. 2022 Source: Immune Thrombocytopenia
Newer Beta Blockers Offered for Use in Atherosclerosis Prevention
An article highlighting recent scientific findings on the beneficial effects of beta-blockers (BB) directly on the arterial wall and the potential benefit for the prevention of atherosclerotic…25. 10. 2022 Source: Cardiovascular Continuum
Will up-titration or combination with bisoprolol help to better control hypertension in amlodipine users?
Will patients with hypertension who do not achieve control of this condition with amlodipine at a dose of 5 mg benefit more from up-titration or combining it with bisoprolol? The answer to this…25. 10. 2022 Source: Cardiovascular Continuum
EMPATHY Questionnaire as a Tool for Better Personalization of Levothyroxine Doses in Patients with Primary Hypothyroidism?
The therapy for hypothyroidism consists of substitution with levothyroxine (L-T4). Failure to achieve the target thyrotropin hormone (TSH) level can be due to non-compliance (in 60% of cases) or…25. 10. 2022 Source: Thyroid Disorders
Can Thyroid Hormone Supplementation Reduce the Risk of Cognitive Disorders?
The recent systematic literature review presented below, published by authors from the California Institute of Behavioral Neurosciences and Psychology (CIBNP), focused, among other things, on…25. 10. 2022 Source: Thyroid Disorders
Administration of RAAS Inhibitors in Czech Patients with Heart Failure in Real Practice
A partial analysis of data from the national register of reimbursed health care focused on the epidemiology of heart failure in the Czech Republic showed how inhibitors of the renin-angiotensin-aldos…24. 10. 2022 Source: Sartans in the Treatment of Hypertension
Robots Performing Blood Draws May Soon Appear in Clinical Practice
Blood draws are undoubtedly among the most common medical procedures in both outpatient and hospital settings. This routine procedure represents a significant time burden for healthcare personnel on…21. 10. 2022 Source: proLékaře.cz
Recent findings on the role and potential of L. reuteri in the therapy of GIT diseases
Probiotics contain bacterial or yeast strains similar to beneficial types naturally occurring in the human gastrointestinal tract. Their role in the therapy of gastrointestinal diseases has been…20. 10. 2022 Source: GI, colic and microbiome
ESC 2022: Can Modern Treatment of Acute Heart Failure Improve (Re)hospitalization Prevention?
Heart failure (HF) and the possibilities of its therapy were one of the frequently discussed topics at this year's annual congress of the European Society of Cardiology (ESC 2022), which took place…19. 10. 2022 Source: Chronic Heart Failure and Lipidology
Diagnosis of AHA Requires Laboratory Testing – What Are Its Key Specifics?
Acquired hemophilia A (AHA) is a rare but very serious disease with a high mortality rate. Quick and accurate diagnosis is crucial, but according to RNDr. Ingrid Hrachovinová, Ph.D., from the…14. 10. 2022 Source: Acquired Hemophilia
The Importance of Hydration in Wound Healing
In response to skin injury, bodily processes initiate to restore the function of the skin barrier, minimize fluid loss, and ensure optimal hydration. Studies have shown that wounds maintained in a…13. 10. 2022 Source: Wound HealingLogin#ADS_BOTTOM_SCRIPTS#Forgotten passwordEnter the email address that you registered with. We will send you instructions on how to set a new password.
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