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Absorption of Levothyroxine: What Has the New Formulation of LT4-Containing Medicinal Products Brought?
Lifelong use of levothyroxine (LT4) is the cornerstone of hypothyroidism treatment. The narrow therapeutic range of LT4 places increased emphasis on accurate dosing and appropriate titration, making the introduction of new LT4 formulations with more precise active ingredient dosing and higher levels of bioequivalence a pathway to facilitate LT4 titration and improve patient adherence.

What situations can arise in PBC treatment with obeticholic acid? Answers provided by case studies from real practice at CKTCH
The Hradec Gastroenterology Days 2023 were traditionally held in March at the Educational Center of…

Subclinical Hypothyroidism in Pregnancy: How Great Are the Real Risks and Can They Be Effectively Reduced?
The aim of the meta-analysis by authors from the Mayo Clinic was to describe the impact of…

Adherence to Treatment of Multiple Sclerosis: How to Enhance It and What Interesting Insights Emerged from Current Research?
Therapeutic options for patients with multiple sclerosis (MS) utilizing disease-modifying drugs (DMDs)...

Teriflunomide in the Treatment of RRMS: The Best Working Drug Is the One That the Patient Actually Takes
Teriflunomide is an oral disease-modifying drug (DMD) used in the therapy of relapsing-remitting multiple...

Early Tumor Regression as a Marker of Overall Survival in First-Line Treatment of mCRC
In the treatment of metastatic colorectal cancer (mCRC), prognostic factors besides overall…

Meta-Analysis of the Results of Studies Comparing the Effectiveness of Manual and Sonic Toothbrushes
Brushing teeth is a fundamental means of maintaining good oral hygiene. While many people still…

Is Obesity a Universal Phenotype in Children with Type 2 Diabetes?
What is the global prevalence of obesity in children and adolescents suffering from type 2 diabetes…

Echocardiography in the Diagnosis of Cardiac Amyloidosis
Cardiac amyloidosis remains a diagnostic challenge that requires great clinical vigilance. The…

Diagnosis and Management of Therapy for a Breastfeeding Patient with Significant Elevation of Liver Enzymes Postpartum – Interactive Case Study
In the following case study, we present a specific approach to a patient who developed a significant...
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