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Efficacy and Safety of Two Pharmacokinetically-Driven Prophylactic Regimens in People with Hemophilia A
Standard prophylaxis for bleeding in hemophilia A, based on the administration of coagulation factor VIII (FVIII), depends on the patient's weight, the severity of the coagulation factor deficiency, and the nature of bleeding episodes. The current trend, however, is an individualized approach in prophylaxis, which can improve clinical outcomes and optimize bleeding disorder therapy. A clinical study evaluated the efficacy and safety of two prophylactic regimens with different target trough levels of FVIII.

How can inosine pranobex help with viral infections?
Inosine pranobex has long been used for its immunomodulatory and antiviral effects in the…

What has clinical research on the effects of inosin pranobex revealed, and what does it mean for practice?
Inosin pranobex, as an antiviral drug that modulates cellular and humoral immunity, is used in the…

Comparison of the Effect of Sonic and Manual Toothbrushes on Dental Plaque and Gingivitis Control
A clinical study on healthy volunteers with mild to moderate gingivitis compared the effectiveness…

Diagnosis of Cow Milk Protein Allergy − Current Methods and Their Diagnostic Value
Cow milk protein allergy (CMPA) is among the most common pediatric food allergies. In case of early…

Etiology and Therapy of Dry Eye Syndrome in a Nutshell
Dry eye syndrome, the most common diagnosis in outpatient ophthalmology practice, is a…

At the Crossroads: 5 Options for Alzheimer's Disease Pharmacotherapy
Currently, we have 5 basic options for the pharmacotherapy of Alzheimer's disease. Is memantine,…

Colours of Sepsis 2023: Antimicrobial Stewardship is a Necessity. The Spectrum of Effective Antimicrobial Modalities has Expanded to Include Another Combination
Inappropriate antibiotic (ATB) treatment is associated with high mortality, while unrestricted use…

Proton radiotherapy means lower risk with high efficacy of radiation. The key is getting the patient into the treatment process as soon as possible
The Proton Therapy Center in Prague (PTC − Proton Therapy Center Czech) is a modern healthcare…

The Unexpected Rise of Telemonitoring During the COVID-19 Pandemic
The COVID-19 pandemic, despite many negative impacts, also brought positive benefits to patients'…
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