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Efficacy and Safety of Two Pharmacokinetically-Driven Prophylactic Regimens in People with Hemophilia A

20. 2. 2023 Source: Hemophilia

Standard prophylaxis for bleeding in hemophilia A, based on the administration of coagulation factor VIII (FVIII), depends on the patient's weight, the severity of the coagulation factor deficiency, and the nature of bleeding episodes. The current trend, however, is an individualized approach in prophylaxis, which can improve clinical outcomes and optimize bleeding disorder therapy. A clinical study evaluated the efficacy and safety of two prophylactic regimens with different target trough levels of FVIII.

infekce

How can inosine pranobex help with viral infections?

Inosine pranobex has long been used for its immunomodulatory and antiviral effects in the…
16. 2. 2023 Source: Viral infections
chripička

What has clinical research on the effects of inosin pranobex revealed, and what does it mean for practice?

Inosin pranobex, as an antiviral drug that modulates cellular and humoral immunity, is used in the…
16. 2. 2023 Source: Viral infections
zubního plaku a gingivitidy

Comparison of the Effect of Sonic and Manual Toothbrushes on Dental Plaque and Gingivitis Control

A clinical study on healthy volunteers with mild to moderate gingivitis compared the effectiveness…
16. 2. 2023 Source: Dental Care
mleko

Diagnosis of Cow Milk Protein Allergy − Current Methods and Their Diagnostic Value

Cow milk protein allergy (CMPA) is among the most common pediatric food allergies. In case of early…
15. 2. 2023 Source: GI, colic and microbiome
Suché oko

Etiology and Therapy of Dry Eye Syndrome in a Nutshell

Dry eye syndrome, the most common diagnosis in outpatient ophthalmology practice, is a…
15. 2. 2023 Source: Ophthalmologic Diseases
alzheimer hlava deda

At the Crossroads: 5 Options for Alzheimer's Disease Pharmacotherapy

Currently, we have 5 basic options for the pharmacotherapy of Alzheimer's disease. Is memantine,…
9. 2. 2023 Source: Viral infections
Colours of Sepsis 20231

Colours of Sepsis 2023: Antimicrobial Stewardship is a Necessity. The Spectrum of Effective Antimicrobial Modalities has Expanded to Include Another Combination

Inappropriate antibiotic (ATB) treatment is associated with high mortality, while unrestricted use…
9. 2. 2023 Source: Anti-Infectives
Protonové centrum

Proton radiotherapy means lower risk with high efficacy of radiation. The key is getting the patient into the treatment process as soon as possible

The Proton Therapy Center in Prague (PTC − Proton Therapy Center Czech) is a modern healthcare…
8. 2. 2023 Source: Proton Radiotherapy
telemonitoring

The Unexpected Rise of Telemonitoring During the COVID-19 Pandemic

The COVID-19 pandemic, despite many negative impacts, also brought positive benefits to patients'…
8. 2. 2023 Source: proLékaře.cz
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