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léky_tablety

Teriflunomide vs. Dimethyl Fumarate: Does Their Classification into Different Treatment Lines Have Merit?

4. 1. 2023 Source: Multiple Sclerosis

Teriflunomide is one of the first-choice medications in the treatment of multiple sclerosis (MS) patients, not only in the Czech Republic. Conversely, the use of dimethyl fumarate is more limited here compared to other countries. Did the data from real-world clinical practice published this year actually demonstrate differences in the efficacy of both medications, and thus justify their classification?

nemocnice příjem čekárna

Prevalence of Heart Failure and Its Subtypes in the Population of Developed Countries

In developed countries, heart failure occurs in approximately 2% of the population, with an annual incidence of 5-10/1000 inhabitants. The mortality rate for patients with chronic heart failure is…
2. 1. 2023 Source: Heart Failure
dyslipidémie

Inclisiran −⁠ a new addition to the arsenal of dyslipidemia treatment

At the XXIX Congress of the Czech Society of Internal Medicine ČLS JEP, held November 6−9, 2022 in Prague, lectures on innovative dyslipidemia therapy using the small interfering RNA molecule −…
23. 12. 2022 Source: Chronic Heart Failure and Lipidology
LDL cholesterol

Use of Inclisiran in a Patient in Secondary Cardiovascular Prevention

Lowering LDL cholesterol (LDL-c) is one of the primary goals for reducing cardiovascular (CV) risk due to its proven mortality reduction. However, many patients with familial hypercholesterolemia or…
23. 12. 2022 Source: Chronic Heart Failure and Lipidology
fokální záchvaty

Cenobamate −⁠ A Case Study from Slovak Real Practice

Cenobamate is indicated for adjunctive therapy of focal seizures with or without secondary generalization in adult patients who have not achieved sufficient results with previous treatment with at…
23. 12. 2022 Source: Epilepsy
karcinom plic_lékař

Brigatinib in the Therapy of Pretreated Patients with Advanced ALK-Positive NSCLC

A French study analyzed clinical data of pretreated ALK-positive patients with advanced non-small cell lung cancer (NSCLC) and examined the efficacy of next-generation ALK inhibitors –⁠ brigatinib,…
22. 12. 2022 Source: Non-Small Cell Lung Cancer
mnohočetný myelom

Addition of ixazomib to lenalidomide and dexamethasone in multiple myeloma −⁠ Data from real-world Czech practice

A group of Czech and Slovak experts led by Associate Professor Jiří Minařík from the Hemato-Oncology Clinic of the Faculty of Medicine UP and University Hospital Olomouc published the final results…
22. 12. 2022 Source: Hematologic Malignancies
Hodgkinovu lymfomu

Consolidation therapy with brentuximab vedotin after autologous stem cell transplantation in patients with relapsed/refractory Hodgkin lymphoma

At the 12th International Symposium on Hodgkin Lymphoma (ISHL), held in October 2022 in Cologne, results of a Czech study evaluating the efficacy and safety of consolidation therapy with brentuximab…
22. 12. 2022 Source: Hematologic Malignancies
srdce a nervy

Role of Transthyretin in the Development of Amyloidosis

Transthyretin (TTR), one of the transport proteins, tends to form extracellular deposits that accumulate in key organs, such as the heart and nerves. The formation of TTR deposits leads to the…
20. 12. 2022 Source: Amyloidosis
Oči_3Dtisk

3D Printing is Already Helping with Eye Prostheses: What Benefits Does the Innovation Offer Patients?

Cosmetic eye prostheses, usually made of glass or acrylic, serve to mask cosmetic defects due to eye damage from various causes. The process of their creation has so far been quite demanding and…
19. 12. 2022 Source: proLékaře.cz
robot v medicíně

Bizarre Technological Innovations in Medicine −⁠ The Dark Side of Progress or the Reality of the Near Future?

A robot drawing blood, meeting the deceased through virtual reality, or a robotic nanny caring for embryos in an artificial womb. Technology has been advancing by leaps and bounds in recent years,…
19. 12. 2022 Source: proLékaře.cz
kapky do očí

Possible Uses of Desodrop in Therapy and Prevention of Ophthalmological Diseases

The medical device Desodrop is the first topical eye preparation based on ozone, intended for the prevention and therapy of eye infections and other diseases. Its efficacy and safety have been…
15. 12. 2022 Source: Treatment of Glaucoma
gastrointestinální trakt

Factors Predicting Longer Survival in Patients with Metastatic Colorectal Cancer Treated with Trifluridine/Tipiracil

A recently published non-interventional analysis evaluated overall survival (OS) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC) with favorable prognostic…
14. 12. 2022 Source: Treatment of Gastrointestinal Carcinomas
omega-3 mastné kyseliny

Impact of Administering Omega-3 Fatty Acids on the Risk of Metabolic Syndrome in Patients with Schizophrenia

The aim of the Polish clinical study OFFER was to assess the possibility of influencing the risk of developing metabolic syndrome (MetS) and some of its individual components in patients with…
13. 12. 2022 Source: Modern Treatment of Schizophrenia
metabolický syndrom

Tool for Predicting Cardiometabolic Risk in Young Patients with Psychotic Disorder

A study describing the development and validation of an algorithm for predicting cardiometabolic risk in patients with psychotic disorder, PsyMetRiC (Psychosis Metabolic Risk Calculator), was…
13. 12. 2022 Source: Modern Treatment of Schizophrenia
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