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Spasmolytic Effect of Metamizole
A study aimed at clarifying the mechanism of action of metamizole suggested that the clinically proven effect of this analgesic on colicky pain originating from the biliary tract could be due to agonism on β2-adrenergic receptors in the smooth muscle of the bile ducts.

PID in children manifest differently, 10 warning signs help in diagnosis
We asked MUDr. Eva Hlaváčková from the Department of Clinical Immunology and Allergology, Faculty…

Can sartans improve clinical outcomes in hypertensive patients with COVID-19?
Dysfunction of the renin-angiotensin system (RAS) has been detected in patients with COVID-19. This…

Candesartan is beneficial in heart failure with mildly reduced ejection fraction
Analysis of data from the CHARM study showed that in patients with heart failure with mildly…

COVID-19 and MS: Do You Know the Risk Factors? What the American Registry Analysis Showed
An article published in the March issue of the prestigious journal JAMA Neurology summarizes the…

Fatigue in Multiple Sclerosis: What Can Teriflunomide Do?
An article by French authors published in January this year in the journal Multiple Sclerosis and…

Long-term effect of the triple combination of perindopril, indapamide, and amlodipine on left ventricular hypertrophy in hypertension
A recent open-label interventional study aimed to describe the long-term effect of a fixed triple…

Myths Accompanying Therapy of Arterial Hypertension
Arterial hypertension is among the most common yet most underestimated diseases in the adult…

Effect of Discontinuing Inhaled Corticosteroids in Patients with COPD in Real Clinical Practice
Inhaled corticosteroids are prescribed to patients with COPD to prevent disease exacerbation.…

Impact of the COVID-19 Pandemic on People with Schizophrenia Spectrum Disorders
The COVID-19 pandemic has a far-reaching impact on the physical and mental health of the global…
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