Search results: (10000)
News Ultrasound in a Patch – Smart System Capable of Monitoring Patient During Regular Activities
A team of scientists from the University of California, San Diego, has developed a miniature autonomous ultrasound system that, when attached to the skin, can visualize tissue located deep beneath the body’s surface. It could be used for continuous monitoring of blood pressure, heart activity, and respiratory parameters in real time, whether during regular activities or intense physical exertion.
News Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract
Brazilian authors published a review of available information on the mechanism of action of metamizole, its impact on gastrointestinal tract motility, its effect on the gastric mucosa, and its antispasmodic effects.
News Care of Dental Dentures According to the Recommendations of the American Society of Dental Prosthetists
Dental dentures are the most common solution for missing teeth in the jaw. They should serve patients for several years, so proper care is essential. Therefore, dental professionals should not only be able to make them perfectly but also provide their patients with quality information about their maintenance. However, individual experts often differ in their recommendations, advising based on their own experiences, and even national dental organizations do not always have these information easily accessible. The American Society of Dental Prosthetists has therefore issued a series of recommendations that can be followed by both doctors and patients or caregivers.
News Prevalence of Heart Failure and Its Subtypes in the Population of Developed Countries
In developed countries, heart failure occurs in approximately 2% of the population, with an annual incidence of 5-10/1000 inhabitants. The mortality rate for patients with chronic heart failure is 7.2% per year, and 31.9% of patients with heart failure are hospitalized annually. Portuguese authors attempted to assess the prevalence of heart failure and its subtypes in a population treated within one healthcare facility over 3 years.
Journal articles Fertility preserving methods in women with breast cancer before gonadotoxic therapy
News Efficacy and Safety of the Combination of Telmisartan and Amlodipine with Hydrochlorothiazide in the Treatment of Hypertension
The aim of the study by Korean authors was to evaluate the efficacy and tolerability of the triple combination of telmisartan/amlodipine + hydrochlorothiazide (TAH) compared to the combination of telmisartan/amlodipine (TA) alone in patients with essential hypertension who did not respond sufficiently to a 4-week treatment with TA.
News Cardio-renal-metabolic syndrome in context
The increase in the incidence of type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), and chronic kidney disease (CKD) ranks among the most significant health issues of our time. Based on recent studies, these conditions are likely interconnected at various levels, whether in epidemiology, pathophysiology, or patient prognosis. Consequently, the term cardio-renal-metabolic syndrome (CRMS) has been defined.
News The Role of the General Practitioner in the Care of Incontinent Patients
General practitioners are sometimes likened to frontline soldiers because they are usually the first to whom patients turn with their health issues. Taking care of incontinent patients is a daily routine for them. They should therefore be knowledgeable about basic diagnostics and treatment and be able to actively identify incontinent patients.
News Therapy with Cyclosporine in the Context of the Coronavirus Pandemic
The rapid spread of the SARS-CoV-2 virus and the associated COVID-19 disease pandemic raises concerns about possible risks associated with immunosuppressive treatment of autoimmune diseases. Specifically, does the use of cyclosporine increase the risk of infection, or does it act protectively?
News Inhibition of Sclerostin in Osteoporosis Therapy
Romosozumab, a subcutaneously administered antibody against sclerostin, is one of the most potent osteoanabolics and appears to be a highly effective modality in the treatment of postmenopausal women's osteoporosis. Essential information about the mechanism of action, insights from completed pivotal studies, and practical recommendations for romosozumab treatment are summarized in the following brief overview.
News Psychotic patient with high cardiometabolic risk – interactive case report
The following case report describes the treatment of a patient diagnosed with paranoid schizophrenia following a relapse of the disease. During therapy, complications arose in the form of weight gain, deterioration of metabolic parameters, sedation, and sexual dysfunction. Additionally, the patient is not capable of adhering to the principles of a healthy lifestyle. Is it possible to find an optimal treatment approach even in such a case?
News INFOGRAPHIC: Diagnostic Algorithm for Cardiac Amyloidosis
What examinations are needed when cardiac amyloidosis is suspected? Which tests can distinguish transthyretin amyloidosis from systemic disease caused by immunoglobulin light chains? We bring you a clear diagnostic scheme according to the recommendations of the European Society of Cardiology (ESC).
.
News How to Detect COPD Early in Primary Care?
Chronic obstructive pulmonary disease (COPD) can be present even in individuals without obvious subjective symptoms, or the emerging symptoms may be overlooked by both the patient and the doctor due to their very gradual development. So, what is the path to early detection of COPD in primary care, and how can this disease be distinguished from others accompanied by similar manifestations?
News Fibrinogen and Management of Peripartum Life-Threatening Hemorrhage
The most common cause of maternal death in the developed world continues to be peripartum life-threatening hemorrhage. It can result as a consequence of the consumption of coagulation factors, primarily fibrinogen. The analysis presented below summarizes information on the prevention of this complication and the use of fibrinogen concentrate therapy.
News Incontinence Affects Mental Health – Actively Offer Help
Urinary incontinence is not a disease, but a symptom accompanying many illnesses. It is a very serious issue, which is also closely related to the quality of life and mental health of the patient. This is confirmed by the words of Austrian physician and co-founder of the field of neurourology Helmut Madersbacher: “Incontinence does not kill a person, but it kills their life.”
News Complex Impacts of Obesity on the Brains of People with Psychiatric Disorders
Obesity in individuals with bipolar disorder or schizophrenia is closely linked not only to higher mortality but also to worse progression of the psychiatric illness, lower response to psychiatric treatment, more frequent fatal outcomes (suicide), deterioration in cognitive functions, and structural brain damage. In his lecture at the XIV Congress of the Psychiatric Society of the Czech Medical Association J.E. Purkyně in Mikulov in June 2022, Professor Tomáš Hájek from Dalhousie University in Halifax, Canada, focused on these connections.
News Reduction of LDL Cholesterol in the Prevention of Cardiovascular Morbidity and Mortality – Results of a Large Meta-Analysis
Elevated LDL cholesterol (LDL-c) is one of the main causes of atherosclerosis. The meta-analysis presented below examined the effect of reducing its levels on the risk of cardiovascular (CV) morbidity and mortality.
News Detection of von Willebrand Disease
Von Willebrand disease (vWD) is an autosomal hereditary bleeding disorder. Its detection and diagnosis require several steps, including the initial suspicion of the presence of this disease.
News Effect of Discontinuing Inhaled Corticosteroids in Patients with COPD in Real Clinical Practice
Inhaled corticosteroids are prescribed to patients with COPD to prevent disease exacerbation. However, in clinical practice, they are often overprescribed in non-indicated cases. A study conducted in real clinical conditions evaluated the effect of discontinuing inhaled corticosteroids compared to continuing triple therapy in patients with COPD.
News Ocrelizumab in the treatment of multiple sclerosis in real-world practice – a systematic review of published studies
In controlled study programs, ocrelizumab has demonstrated beneficial effects on improving clinical parameters in patients with multiple sclerosis, such as the annual relapse rate or confirmed disability progression. However, to get a complete picture of its clinical benefit, real-world evidence in a broad patient population is also needed. A systematic review of real-world clinical practice studies with ocrelizumab, published in March 2023, demonstrates its benefits in patients with relapsing-remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS) in terms of relapse frequency, disease activity on MRI, disability, absence of disease activity (NEDA), and quality of life.
News Which Dietary Recommendations Actually Work for Irritable Bowel Syndrome?
Food is both a trigger for symptoms and a treatment tool for individuals with irritable bowel syndrome (IBS). A 2021 review summarizes the results of the latest research on the effectiveness of dietary measures for IBS and the evidence of which measures are truly beneficial. A positive impact was found for general healthy eating recommendations, soluble fiber supplementation, a low short-chain carbohydrate diet, and probiotic administration.
News Immunotherapy of Cancer Diseases
Immunotherapeutic strategies have been successfully utilized recently in the treatment of various malignancies. Increasing understanding of the interactions between the tumor and the host organism over the last few years has led to proposals of various promising therapeutic approaches. This overview briefly summarizes the basic principles of immunotherapy for cancer diseases.