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News When and why to consider the diagnosis of myasthenia gravis in neurological practice, and what treatment options do we currently have?
Myasthenia gravis (MG) is a clinically heterogeneous disease characterized by fluctuating muscle weakness and fatigability that worsens after physical exertion or mental stress. Accurate diagnosis is essential because treatment can lead to permanent remission and full functional capacity of the patient.
News More Patients Will Now Have Access to Incontinence Aids
Since December of last year, new rules have been in effect for the prescription of medical aids prescribed through vouchers, including aids for urine collection and voiding. The new rules are governed by the current wording of Act No. 48/1997 Coll., on Public Health Insurance, which also includes a new categorization tree (Appendix No. 3 to the Act).
News Levodropropizine – a non-codeine antitussive with minimal side effects, contraindications, and drug interactions
For symptomatic treatment of dry, irritating, and exhausting cough, both codeine and non-codeine antitussives can be used. One of the non-codeine antitussives is levodropropizine. Its antitussive effect is comparable to centrally acting codeine antitussives, but with a significantly lower incidence of side effects. Compared to codeine, it has a much narrower range of contraindications, and no interactions with benzodiazepines or drugs used in the treatment of bronchopulmonary diseases have been observed.
News Use of Tiapride in the Treatment of Behavioral Disorders in Geriatric Patients
Hand in hand with the increasing number of people reaching an older age, there is also a rise in the occurrence of dementia. It affects the lives of patients and their families in many ways. A significant problem can be behavioral disorder, which needs to be treated adequately and promptly to prevent issues such as injuries.
News Trazodone as an Effective Medicine in the Therapy of Depression and Insomnia
Trazodone (Trittico®) is a medicine indicated for the treatment of depression, which has also been shown to have a positive effect in treating other associated conditions. In practice, however, the potential of its multimodal effect sometimes remains untapped.
News The Wound Healing Process Step by Step and What Can Complicate It
Proper care of injuries is a fundamental prerequisite for their successful healing. Knowing the individual phases of healing facilitates treatment and helps prevent the most common complications.
News Will 3D Printable Tissue Adhesives Replace Stitches and Clips?
3D printing technology is slowly making its way into more and more areas of healthcare. In February 2024, a scientific team from the Massachusetts Institute of Technology (MIT) published a study in the journal Nature Communications focusing on the possibilities of 3D printing tissue adhesives and personalized patches with adjustable internal structures. These could therefore become a suitable alternative to the traditional surgical sutures and clips used for joining tissues.
Journal articles Transcranial sonography of the medial temporal lobe in Alzheimer’s disease patients
News Thyroid Function During COVID-19 Illness and After Recovery
Acute infection with the SARS-CoV-2 coronavirus has varying impacts on different organ systems of the human body. Until now, it has not been certain how precisely it affects the endocrine system, especially the thyroid gland. The study presented below investigated how thyroid function changes in relation to the course of COVID-19 infection.
News Pain Management After Day Surgery
Effective pain control is a crucial part of recovery for patients after painful surgical procedures. In clinical practice, combined analgesia using paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) is commonly utilized, which, however, is not suitable for up to a quarter of patients. An alternative could be metamizole. A study published in the European Journal of Anaesthesiology evaluated the non-inferiority of the combination of paracetamol/metamizole versus paracetamol/ibuprofen in pain management for patients after day surgery.
News Long-term Safety of Dupilumab in Adult Patients with Moderate to Severe Atopic Dermatitis
Moderate to severe atopic dermatitis (AD) often requires systemic therapy. The long-term safety of dupilumab in patients with this condition was evaluated in an open-label extension (OLE) of the LIBERTY AD study, the results of which were recently published.
News Aloe vera Extract in the Therapy of Irritable Bowel Syndrome
The therapy options for irritable bowel syndrome are relatively limited, thus complementary and alternative treatments besides conventional therapy are applied. Many patients report that using Aloe vera extract helps reduce their disease symptoms, although there is a lack of valid evidence from clinical studies. The pilot study presented below focused on evaluating the efficacy of Aloe vera extract compared to placebo in several dozen patients with irritable bowel syndrome.
News INFOGRAPHIC: LDL Cholesterol - Recommended Target Values
Elevated levels of LDL cholesterol are a significant risk factor for cardiovascular diseases, which remain the most common cause of death among adult Czechs. We have strong evidence about who and how LDL-c should be reduced, and ample treatment options to achieve this. Yet, more than half of the patients do not achieve the target LDL-c values. A useful tool for practice can be the 'risk traffic light' - an infographic clearly showing which risk category a patient falls into and what the recommended target LDL-c values are for each risk category. This makes it easier to plan tailor-made individual treatment.
News Options for Preventing Enteral Nutrition Intolerance in Mechanically Ventilated Patients in the ICU
Standards of care for critically ill patients recommend enteral nutrition for those on mechanical ventilation. A recently published study addressed the question of how to identify patients at risk of enteral nutrition intolerance (ENI) and how to subsequently prevent this intolerance, which may be associated with worse clinical outcomes.
News The Role of the General Practitioner in the Care of Incontinent Patients
General practitioners are sometimes likened to frontline soldiers because they are usually the first to whom patients turn with their health issues. Taking care of incontinent patients is a daily routine for them. They should therefore be knowledgeable about basic diagnostics and treatment and be able to actively identify incontinent patients.
News Urinary Incontinence in Old Age as the Most Frequent Medical Problem
In patients over 65 years of age, incontinence occurs more frequently than cancer or cardiovascular diseases. Urine leakage significantly reduces the quality of life for seniors, worsens their overall health, and isolates them from society. Therefore, doctors should participate in destigmatizing this problem and actively offer their help to seniors and their family members.
News The Patient Will Feel Comfortable Only with a Properly Chosen Absorption Aid
While before the approval of the amendment to the Public Health Insurance Act, it was possible to issue a prescription only for one type of aid firmly tied to a particular level of incontinence, now it is allowed to freely combine aids according to the individual needs of the patient. The modern market offers a wide range of aids − but how to choose a product that matches specific needs?
News Incontinence Affects Mental Health – Actively Offer Help
Urinary incontinence is not a disease, but a symptom accompanying many illnesses. It is a very serious issue, which is also closely related to the quality of life and mental health of the patient. This is confirmed by the words of Austrian physician and co-founder of the field of neurourology Helmut Madersbacher: “Incontinence does not kill a person, but it kills their life.”
News AI Could Transform Cancer Treatment by Precisely Identifying Tumor Cells
A new artificial intelligence tool called AAnet, developed and tested by researchers led by the Garvan Institute of Medical Research, focuses on the cellular diversity within individual tumors. Deeper understanding of the different types of cells present in tumors could pave the way for therapies more accurately tailored to individual patients.
News Inosine Pranobex in the Treatment of Cervical HPV Infections
The aim of the review article published in the journal Infection and Drug Resistance was to evaluate the available data on the potential use of inosine pranobex in the treatment of patients with a positive human papillomavirus finding in a cervical smear.
News Side Effects of Metformin: It's Not Just a Nocebo Effect?
If we were to name medications that have the greatest significance from a population standpoint, metformin would certainly be at the top of the list. We have known it for over fifty years and know a lot about it, including its negatives. But is it time to replace it with new drugs? Or is it worth staying with it?