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News The Wound Healing Process Step by Step and What Can Complicate It

Proper care of injuries is a fundamental prerequisite for their successful healing. Knowing the individual phases of healing facilitates treatment and helps prevent the most common complications.
Source: Wound Healing 2. 12. 2020

News Will 3D Printable Tissue Adhesives Replace Stitches and Clips?

3D printing technology is slowly making its way into more and more areas of healthcare. In February 2024, a scientific team from the Massachusetts Institute of Technology (MIT) published a study in the journal Nature Communications focusing on the possibilities of 3D printing tissue adhesives and personalized patches with adjustable internal structures. These could therefore become a suitable alternative to the traditional surgical sutures and clips used for joining tissues.
Source: 8. 5. 2024

Journal articles Transcranial sonography of the medial temporal lobe in Alzheimer’s disease patients

Author of the article: D. Školoudík, P. Krulová, H. Kisvetrová, R. Herzig, J. Blahuta, T. Soukup Source: Česká a slovenská neurologie a neurochirurgie | 2/2020 8. 4. 2020

News Thyroid Function During COVID-19 Illness and After Recovery

Acute infection with the SARS-CoV-2 coronavirus has varying impacts on different organ systems of the human body. Until now, it has not been certain how precisely it affects the endocrine system, especially the thyroid gland. The study presented below investigated how thyroid function changes in relation to the course of COVID-19 infection.
Source: Thyroid Disorders 6. 5. 2021

News Pain Management After Day Surgery

Effective pain control is a crucial part of recovery for patients after painful surgical procedures. In clinical practice, combined analgesia using paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) is commonly utilized, which, however, is not suitable for up to a quarter of patients. An alternative could be metamizole. A study published in the European Journal of Anaesthesiology evaluated the non-inferiority of the combination of paracetamol/metamizole versus paracetamol/ibuprofen in pain management for patients after day surgery.
Source: Analgesia 21. 4. 2022

Journal articles Non-Hodgkin lymphomas in the Czech Republic

Author of the article: M. Trněný Source: Transfuze a hematologie dnes | 1/2019 29. 3. 2019

Journal articles Sexual Dysfunction and its Incidence in Patients with Epilepsy

Author of the article: R. Mařák, M. Pohanka, K. Langová, J. Zapletalová, R. Herzig, P. Kaňovský Source: Česká a slovenská neurologie a neurochirurgie | 3/2010 24. 6. 2010

Journal articles Balance disorders in patients with multiple sclerosis and possible rehabilitation therapy –⁠ current findings from controlled clinical trials

Author of the article: K. Novotná-, I. Menkyová, M. Janatová Source: Česká a slovenská neurologie a neurochirurgie | 2/2022 15. 5. 2022

News Long-term Safety of Dupilumab in Adult Patients with Moderate to Severe Atopic Dermatitis

Moderate to severe atopic dermatitis (AD) often requires systemic therapy. The long-term safety of dupilumab in patients with this condition was evaluated in an open-label extension (OLE) of the LIBERTY AD study, the results of which were recently published.
Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation 24. 1. 2023

News Aloe vera Extract in the Therapy of Irritable Bowel Syndrome

The therapy options for irritable bowel syndrome are relatively limited, thus complementary and alternative treatments besides conventional therapy are applied. Many patients report that using Aloe vera extract helps reduce their disease symptoms, although there is a lack of valid evidence from clinical studies. The pilot study presented below focused on evaluating the efficacy of Aloe vera extract compared to placebo in several dozen patients with irritable bowel syndrome.
Source: Irritable Bowel Syndrome 12. 10. 2022

News INFOGRAPHIC: LDL Cholesterol -⁠ Recommended Target Values

Elevated levels of LDL cholesterol are a significant risk factor for cardiovascular diseases, which remain the most common cause of death among adult Czechs. We have strong evidence about who and how LDL-c should be reduced, and ample treatment options to achieve this. Yet, more than half of the patients do not achieve the target LDL-c values. A useful tool for practice can be the 'risk traffic light' -⁠ an infographic clearly showing which risk category a patient falls into and what the recommended target LDL-c values are for each risk category. This makes it easier to plan tailor-made individual treatment.
Source: Chronic Heart Failure and Lipidology 11. 6. 2021

News Options for Preventing Enteral Nutrition Intolerance in Mechanically Ventilated Patients in the ICU

Standards of care for critically ill patients recommend enteral nutrition for those on mechanical ventilation. A recently published study addressed the question of how to identify patients at risk of enteral nutrition intolerance (ENI) and how to subsequently prevent this intolerance, which may be associated with worse clinical outcomes.
Source: Enteral Nutrition 12. 4. 2021

News The Role of the General Practitioner in the Care of Incontinent Patients

General practitioners are sometimes likened to frontline soldiers because they are usually the first to whom patients turn with their health issues. Taking care of incontinent patients is a daily routine for them. They should therefore be knowledgeable about basic diagnostics and treatment and be able to actively identify incontinent patients.
Source: Incontinence 2. 6. 2020

News Urinary Incontinence in Old Age as the Most Frequent Medical Problem

In patients over 65 years of age, incontinence occurs more frequently than cancer or cardiovascular diseases. Urine leakage significantly reduces the quality of life for seniors, worsens their overall health, and isolates them from society. Therefore, doctors should participate in destigmatizing this problem and actively offer their help to seniors and their family members.
Source: Incontinence 9. 9. 2020

News The Patient Will Feel Comfortable Only with a Properly Chosen Absorption Aid

While before the approval of the amendment to the Public Health Insurance Act, it was possible to issue a prescription only for one type of aid firmly tied to a particular level of incontinence, now it is allowed to freely combine aids according to the individual needs of the patient. The modern market offers a wide range of aids −⁠ but how to choose a product that matches specific needs?
Source: Incontinence 27. 2. 2020

News Incontinence Affects Mental Health –⁠ Actively Offer Help

Urinary incontinence is not a disease, but a symptom accompanying many illnesses. It is a very serious issue, which is also closely related to the quality of life and mental health of the patient. This is confirmed by the words of Austrian physician and co-founder of the field of neurourology Helmut Madersbacher: “Incontinence does not kill a person, but it kills their life.”
Source: Incontinence 3. 6. 2020

News AI Could Transform Cancer Treatment by Precisely Identifying Tumor Cells

A new artificial intelligence tool called AAnet, developed and tested by researchers led by the Garvan Institute of Medical Research, focuses on the cellular diversity within individual tumors. Deeper understanding of the different types of cells present in tumors could pave the way for therapies more accurately tailored to individual patients.
Source: 10. 9. 2025

News Inosine Pranobex in the Treatment of Cervical HPV Infections

The aim of the review article published in the journal Infection and Drug Resistance was to evaluate the available data on the potential use of inosine pranobex in the treatment of patients with a positive human papillomavirus finding in a cervical smear.
Source: Viral infections 13. 7. 2022

News Association of Low TSH Levels in Hypothyroidism Therapy with Mortality Risk

Community surveys indicate that up to 53% of patients treated for hypothyroidism have serum thyroid-stimulating hormone (TSH) levels outside the normal range at some point. The negative effect of TSH levels above the upper reference limit is well documented, but according to two recently published population studies, mortality in patients treated with levothyroxine is also increased when TSH levels are below the lower reference limit.
Source: Thyroid Disorders 14. 9. 2022

Journal articles Autoimmune liver diseases in children. Part II

Author of the article: P. Dědek Source: Česko-slovenská pediatrie | 1/2011 3. 1. 2011

News What has clinical research on the effects of inosin pranobex revealed, and what does it mean for practice?

Inosin pranobex, as an antiviral drug that modulates cellular and humoral immunity, is used in the treatment of many viral infections. It is employed in diseases caused by herpetic viruses, Epstein-Barr virus (EBV), cytomegalovirus, or in immunodeficient states, especially in cases of cellular immunity disorders. What insights has clinical research offered on this matter?
Source: Viral infections 16. 2. 2023

Journal articles

Author of the article: Pavol Holéczy, Matej Pekař, Marek Bužga, Eva Evinová Source: Časopis lékařů českých | 3-4/2022 12. 9. 2022

Journal articles Guidelines of the Czech Society of Hepatology for diagnosis and treatment of primary biliary cholangitis

Author of the article: T. Fejfar, T. Vaňásek, P. Hůlek, L. Vítek, S. Fraňková, R. Brůha Source: Gastroenterologie a hepatologie | 2/2018 4. 5. 2018

News Complete remission of ALK-positive lung cancer in a patient after multiple lines of targeted therapy –⁠ a case study

Targeted treatment for driving oncogenic mutations has significantly improved outcomes for patients with ALK-positive non-small cell lung cancer (NSCLC) as well. A case study was recently published in the journal Frontiers in Oncology of a patient with advanced disease who achieved complete remission after several lines of therapy.
Source: Genetic Profile and Treatment of NSCLC 27. 12. 2021

News Effect of Itopride on Esophageal Motility and Lower Esophageal Sphincter Function

Itopride is a prokinetic used in the therapy of functional non-ulcerous upper dyspeptic difficulties. The mechanism of action involves inhibition of acetylcholinesterase and antagonism at dopamine D2 receptors. A clinical study by Belgian authors from the Catholic University of Leuven evaluated whether the effect of itopride is due to its influence on esophageal motility and lower esophageal sphincter function.
Source: Gastrointestinal Treatment 21. 4. 2020

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