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News Finger on the Pulse of the Times with Automated Peritoneal Dialysis and Remote Patient Monitoring

The method of peritoneal dialysis brings many advantages to patients with chronic kidney disease and significantly eases their lives. Peritoneal dialysis saves time for both the patients themselves and the attending healthcare personnel. Modern medicine now offers an innovative tool that can remotely monitor the patient's condition, with the possibility of adjusting the treatment regimen.

Source: Chronic Kidney Disease 29. 9. 2020

News KDIGO: The Choice of Dialysis Modality Must Consider Patient Individuality

The moment of initiating dialysis, as well as the period immediately before and after it, is crucial for good treatment outcomes. But what exactly can be considered a good outcome, and do the perspectives of doctors and patients align on this issue? Leading nephrologists worldwide discussed this at the KDIGO conference, which was specifically focused on controversies in dialysis treatment.

Source: Chronic Kidney Disease 27. 5. 2020

Články časopisu Acute kidney injury in patients with acute pancreatitis

Author of the article: N. Petejová, Arnošt Martínek, V. Teplan Source: Gastroenterologie a hepatologie | 2/2018 4. 5. 2018

News Teriflunomide and Pregnancy Planning

The authors of the article published last year in Multiple Sclerosis Journal present data regarding experiences with the use of teriflunomide during pregnancy.

Source: Multiple Sclerosis 25. 3. 2021

News Current Findings on Fixed Combination Aclidinium/Formoterol in COPD Therapy

The fixed inhalation combination of aclidinium/formoterol represents a combination of a long-acting anticholinergic (LAMA) and a long-acting β₂-mimetic (LABA) used for maintenance treatment of moderate to severe chronic obstructive pulmonary disease (COPD). Below, we summarize the current findings on the efficacy and safety of this dual bronchodilation therapy.

Source: Treatment of Asthma and COPD 30. 8. 2022

News What FVIII Levels Are Ideal for Preventing Bleeding in Hemophilia A?

Recent studies indicate that target trough levels of factor 1–3% during prophylactic treatment are insufficient to fully prevent clinical and subclinical bleeding. With a sustained FVIII level > 15%, as shown in studies with mild hemophiliacs, spontaneous bleeding is very rare. This raises the question of whether achieving zero bleeding incidence with FVIII replacement therapy is possible and whether it can be a realistic goal. This topic was also explored in a presentation by Dr. Ester Zápotocká from the Clinic of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and Motol University Hospital in Prague.

Source: Hemophilia 10. 5. 2021

News Combined Hormonal Contraception in the Treatment of Dysmenorrhea

Dysmenorrhea troubles many women of reproductive age and can deteriorate their quality of life, making it important for doctors to offer suitable therapy. We summarize the findings of research on the use of hormonal contraception containing drospirenone (DRSP) and ethinylestradiol (EE) in the treatment of dysmenorrhea.

Source: Oral Contraception 15. 3. 2022

News Case Study with Voting: Intensification of Type 2 Diabetes Therapy in a Chronically Treated Patient. How to Proceed According to Current Recommendations?

We have prepared an interactive case study for you with a 70-year-old patient with decompensated Type 2 Diabetes. The patient was diagnosed with DM eight years ago. What treatment approach would you choose? And why? And how should you correctly proceed according to the current recommendations of SVL? Watch a short video with us.

Source: Diabetes 12. 11. 2020

Články časopisu Type 2 diabetes mellitus and bone quality

Author of the article: MUDr. Raška Ivan, Ph.D. Source: Clinical Osteology | 3/2018 14. 5. 2019

News Overview of the Efficacy of the Fixed Combination Aclidinium-Bromide/Formoterol-Fumarate in the Maintenance Treatment of COPD

Fixed combination inhalation medications have become the cornerstone of pharmacotherapy for moderate to severe chronic obstructive pulmonary disease (COPD). American authors have published an overview of study results evaluating the efficacy and safety of one of the newest fixed combinations of LABA/LAMA, aclidinium-bromide and formoterol-fumarate (AB/FF), in the maintenance treatment of COPD compared to placebo or other medications. These clinical studies investigated the extent to which regular use of this fixed combination alleviates COPD symptoms, improves lung function, reduces the incidence of exacerbations, and increases exercise tolerance.

Source: Treatment of Asthma and COPD 30. 8. 2022

Články časopisu Novel molecules used in the targeted treatment of acute myeloid leukaemia –⁠ adverse reactions, treatment complications and signifi cant drug interactions

Author of the article: J. Vedrová, Z. Ráčil Source: Transfuze a hematologie dnes | 1/2021 15. 3. 2021

News 48 Tablets of Teriflunomide? Nothing Should Be Overdone! −⁠ Case Study

A case study published in the Journal of Clinical Pharmacy and Therapeutics describes an overdose of teriflunomide, specifically the ingestion of 672 mg of this drug. What measures did the doctors take with the patient? And were they able to prevent serious consequences?

Source: Multiple Sclerosis 15. 8. 2023

Články časopisu The EMPRISE study (Real World Evidence): empagliflozin is reducing number of hospitalizations for heart failure, even in patients without cardiovascular disease

Author of the article: Emil Martinka Source: Forum Diabetologicum | 3/2019 18. 12. 2019

Články časopisu Extrahepatic bile duct malignancies

Author of the article: V. Třeška, J. Fichtl, J. Ferda, J. Fínek, T. Skalický, V. Liška, P. Hošek Source: Rozhledy v chirurgii | 9/2022 17. 10. 2022

News Effect of Extended-Release Metformin on Cognitive Functions in Older Frail Women with Diabetes and Hypertension

Women have a higher risk of geriatric frailty regardless of age and menopausal status. This risk further increases with the presence of diabetes and hypertension, which also elevate the risk of cognitive dysfunction. According to available data, metformin may reduce the risk of developing frailty in postmenopausal women. A recently published Italian study, LEOPARDESS, aimed to evaluate the effect of extended-release metformin on the cognitive functions of this population of women.

Source: Cardiovascular Risks 14. 3. 2024